| antibody | Antibody Description | Target | Target Description | Vendor ID | Lab | Documents | Lots | Target Link | Label | |
|---|---|---|---|---|---|---|---|---|---|---|
| ARID3A_(NB100-279) | Rabbit polyclonal affinity purified antibody. Immunogen: A synthetic peptide, which represented a portion of human Dead Ringer-Like 1 encoded within exon 8. Antibody Target: ARID3A | ARID3A | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. (provided by RefSeq) | Novus Biologicals NB100-279 | Snyder | Human - ARID3A (NB100-279)(Immunoprecipitation,ChIP-seq) | A1 | GeneCard:ARID3A | ARID3A (NB100-279) | |
| ARID3A_(sc-8821) | Goat polyclonal affinity purified antibody raised against a peptide mapping at the N-terminus of ARID3A of human origin. Antibody Target: ARID3A | ARID3A | This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. (provided by RefSeq) | Santa Cruz Biotechnology sc-8821 | Snyder | Human - ARID3A (sc-8821)(Immunoprecipitation,ChIP-seq) | B100 | GeneCard:ARID3A | ARID3A (sc-8821) | |
| ATF1_(06-325) | Sheep polyclonal protein A/G affinity purified, immunogen: CPVTLTSQTTKTDDPQL. Antibody Target: ATF1 | ATF1 | ATF1 is a bZip transcription factor from the CREB family. ATF1 binds to both cAMP response elements (TGACGTCA). | Millipore 06-325 | Struhl | Human - ATF1 (06-325)(Western blot,ChIP-seq) | GeneCard:ATF1 | ATF1 (06-325) | ||
| ATF2_(9221) | Rabbit polyclonal, antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2. Antibodies are purified by protein A and peptide affinity chromatography. Antibody Target: ATF2 | ATF2 | ATF2 is a stress inducible basic leucine zipper transcription factor from the CREB family. ATF2 is phosphorylated at threonine residues 69 and 71 by JNK or p38 mitogen activated protein kinases. Mutation of these residues leads to the loss of ATF2 transactivation in vitro. | Cell Signaling Technology 9221 | Struhl | Human - ATF2 (9221)(Western blot,Immunoprecipitation) | GeneCard:ATF2 | ATF2 (9221) | ||
| ATF2_(sc-6233) | Rabbit polyclonal protein A/G affinity purified, epitope corresponding to amino acids 1-96 mapping at the N-terminus of ATF-2 of human origin. Antibody Target: ATF2 | ATF2 | ATF2 is a bZip transcription factor from the CREB family. ATF2 binds to both cAMP response elements (TGACGTCA) and TPA responsive element (TGAGTCA) and is known to heterodimerize with JUN members of the AP1 family of transcription factors. ATF2 is activated by phosphorylation of Thr71 by the stress activated p38 mitogen activated protein kinases. | Santa Cruz Biotechnology sc-6233 | Struhl | Human - ATF2 (sc-6233)(Western blot,ChIP-seq) | GeneCard:ATF2 | ATF2 (sc-6233) | ||
| ATF2_(SC-81188) | Mouse monoclonal IgG, raised against a recombinant protein corresponding to an internal region of ATF2 of human origin. Antibody Target: ATF2 | ATF2 | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. (provided by RefSeq) | Santa Cruz Biotechnology sc-81188 | Myers | Human - ATF2 (sc-81188)(Western blot,IP-MassSpec) | H0609 | GeneCard:ATF2 | ATF2 (sc-81188) | |
| ATF3 | Rabbit polyclonal IgG, epitope mapping at the C-terminus of ATF3 of human origin. Antibody Target: ATF3 | ATF3 | Activating transcription factor 3. A bZIP transcription factor and member of the Ca2+/cAMP response element-binding (CREB) protein family. ATF3 is found to act both as an activator and repressor of transcription. | Santa Cruz Biotechnology sc-188 | Myers | Human - ATF3(sc-188)(Immunoblot) | J2209 E1406 | GeneCard:ATF3 | ATF3 (sc-188) | |
| Bach1_(sc-14700) | Goat polyclonal. BACH1 (C-20) is an affinity purified antibody raised against a peptide mapping near the C-terminus of BACH1 of human origin. Antibody Target: BACH1 | BACH1 | This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. (provided by RefSeq) | Santa Cruz Biotechnology sc-14700 | Snyder | Human - Bach1 (sc-14700)(Immunoblot,IP-MassSpec) | E1503 | GeneCard:BACH1 | BACH1 (sc-14700) | |
| BATF | Mouse monoclonal. Raised against recombinant B-ATF of human origin. Antibody Target: BATF | BATF | The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. | Santa Cruz Biotechnology sc-100974 | Myers | Human - BATF(sc-100974)(Western blot) | D0808 | GeneCard:BATF | BATF (sc-100974) | |
| BCL11A | Mouse monoclonal [18B12DE6] to Ctip1. Raised against a cocktail of BCL11A fusion proteins. Antibody Target: BCL11A | BCL11A | This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis,is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity) | abcam ab19489 | Myers | Human - missing | GeneCard:BCL11A | BCL11A (ab19489) | ||
| BCL11A_(SC-56011) | Mouse monoclonal IgG, raised against BCL11A of human origin. Antibody Target: BCL11A | BCL11A | This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. (provided by RefSeq) | Santa Cruz Biotechnology sc-56011 | Myers | Human - BCL11A (sc-56011)(Western blot,IP-MassSpec) | B2811 | GeneCard:BCL11A | BCL11A (sc-56011) | |
| BCL3 | Rabbit polyclonal. Bcl-3(C-14) is an affinity purified antibody raised against a peptide mapping at the C-terminus of Bcl-3 of human origin. Antibody Target: BCL3 | BCL3 | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. (Provided by RefSeq). | Santa Cruz Biotechnology sc-185 | Myers | Human - BCL3(Immunoblot) | GeneCard:BCL3 | BCL3 (sc-185) | ||
| BCLAF1_(SC-101388) | Mouse monoclonal IgG, raised against a synthetic peptide corresponding to a.a. 900-909 of BCLAF1 of human origin. Antibody Target: BCLAF1 | BCLAF1 | This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins (RefSeq). | Santa Cruz Biotechnology sc-101388 | Myers | Human - BCLAF1(sc-101388)(Immunoblot,Western blot) | GeneCard:BCLAF1 | BCLAF1 (sc-101388) | ||
| BDP1 | Rabbit polyclonal - Antiserum 2663 was raised by immunizing rabbits with synthetic peptide CSDRYRIYKAQKLRE (human Bdp1 residues 139?153) coupled to KLH. Antibody Target: BDP1 | BDP1 | 'B double-prime 1', subunit of RNA polymerase III transcription initiation factor IIIB | Dr. Robert J. White at Beatson Institute for Cancer Research 2663 | Struhl | Human - BDP1(2663)(IP-MassSpec,Correlation) | GeneCard:BDP1 | BDP1 (2663) | ||
| BHLHE40 | Mouse monoclonal. Dec-1(S-8) is an IgG2b antibody raised against recombinant DEC1 of human origin. Antibody Target: BHLHE40 | BHLHE40 | This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation. | Santa Cruz Biotechnology sc-101023 | Myers, Snyder | Human - BHLHE40(Immunoblot) | GeneCard:BHLHE40 | BHLHE40 (sc-101023) | ||
| BHLHE40_(NB100-1800) | Rabbit polyclonal, maps to a region between residues 350 and the C-terminus (residue 412). Antibody Target: BHLHE40 | BHLHE40 | This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation. | Novus Biologicals NB100-1800 | Snyder | Human - BHLHE40 (NB100-1800)(Immunoprecipitation,IP-MassSpec)
Mouse- BHLHE40 (NB100-1800)(Immunoprecipitation,IP-MassSpec) |
A1 | GeneCard:BHLHE40 | BHLHE40 (NB100-1800) | |
| BRCA1_(A300-000A) | Rabbit polyclonal recognizing a region between residue 1800 and the C-terminus (residue 1863) of human Breast Cancer Gene 1. Antibody Target: BRCA1 | BRCA1 | Nuclear phosphoprotein that plays a role in maintaining genomic stability, and acts as a tumor suppressor. Associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. Plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. | Bethyl Laboratories A300-000A | Snyder | Human - BRCA1 (A300-000A)(Western blot,IP-MassSpec) | GeneCard:BRCA1 | BRCA1 (A300-000A) | ||
| BRF1 | Rabbit polyclonal - Anti-BRF antibody 128 was raised by immunising rabbits with synthetic peptide KISSKINYSVLRGLS (human BRF residues 533-547) coupled to keyhole limpet haemocyanin. Antibody Target: BRF1 | BRF1 | 'B-related factor 1', subunit of RNA polymerase III transcription initiation factor IIIB | Dr. Robert J. White at Beatson Institute for Cancer Research 128 | Struhl | Human - BRF1(128)(IP-MassSpec,Correlation) | GeneCard:BRF1 | BRF1 (128) | ||
| BRF2 | Rabbit polyclonal raised by immunizing rabbits with keyhole limpet hemocyanin coupled to synthetic peptides VSRSQQRGLRRVRDLC and SDSEIEQYLRTPQEVR, corresponding to human Brf2 residues 66-80 and 385-400, respectively. Antibody Target: BRF2 | BRF2 | Brf2 is a component of an alternate form of the RNA Polymerase III transcription factor TFIIIB. | Dr. Robert J. White at Beatson Institute for Cancer Research 4295 | Struhl | Human - BRF2(4295)(Western blot,Correlation) | GeneCard:BRF2 | BRF2 (4295) | ||
| BTF3_(SC-166093) | Mouse monoclonal IgG, raised against amino acids 1-206 representing full length BTF3a of human origin. Antibody Target: BTF3 | BTF3 | This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. (provided by RefSeq) | Santa Cruz Biotechnology sc-166093 | Myers | Human - BTF3 (sc-166093)(Western blot,IP-MassSpec) | G2209 | GeneCard:BTF3 | BTF3 (sc-166093) | |
| CBX2 | Rabbit polyclonal Antigen Affinity Purified, Unconjugated. Antibody Target: CBX2 | CBX2 | Chromobox protein homolog 2 is a component of the polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P19474] | Bethyl Laboratories A302-524A | Bernstein | Human - CBX2 (A302-524A)(ChIP-seq,Western blot) | A302-524A-1 | GeneCard:CBX2 | CBX2 (A302-524A) | |
| CBX3_(SC-101004) | Mouse monoclonal IgG, raised against recombinant CBX3 of human origin. Antibody Target: CBX3 | CBX3 | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene. | Santa Cruz Biotechnology sc-101004 | Myers | Human - CBX3 (sc-101004)(Western blot,IP-MassSpec) | G1410 | GeneCard:CBX3 | CBX3 (sc-101004) | |
| HP1gamma_(ab10480) | Rabbit polyclonal affinity purified to a synthetic peptide conjugated to KLH, derived from within residues 1 - 100 of Mouse HP1 gamma Antibody Target: CBX3 | CBX3 | CBX3 seems to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. It may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). | abcam ab10480 | Bernstein | Human - HP1gamma (ab10480)(ChIP-seq,Western blot) | GR22075-1 | GeneCard:CBX3 | HP1gamma (ab10480) | |
| CBX8 | Rabbit polyclonal antigen affinity purified, Unconjugated Antibody Target: CBX8 | CBX8 | CBX8 is part of the polycomb group of proteins that are important in embryogenesis and human tumorigenesis and regulates a number of genes involved in cell growth and survival. There are at least 5 CBX proteins in mammals. CBX proteins associate with the core polycomb repressive complex 1 (PRC1) that functions to maintain the transcriptionally repressive state of genes during development. | Bethyl Laboratories A300-882A | Bernstein | Human - CBX8 (A300-882A)(ChIP-seq,Western blot) | A300-882A-1 | GeneCard:CBX8 | CBX8 (A300-882A) | |
| CycT1_(sc-10750) | Rabbit polyclonal A/G affinity purified, epitope corresponding to amino acids 261-505 mapping to an internal region of cyclin T1 (CycT1) of human origin. Antibody Target: CCNT1 | CCNT1 | Cyclin T1 is a cyclin that forms heterodimers with the cyclin dependent kinase CDK9. CDK9 is responsible for phosphorylating Ser2 of the heptad repeat of the C-terminal domain of the large subunit of RNA polymerase II, and negative elongation factors NELF and DSIF. Cyclin T1 makes contacts with RNAPII and nascent mRNA and as such recruits CDK9 to facilitate release of stalled RNAPII and productive elongation. | Santa Cruz Biotechnology sc-10750 | Struhl | Human - CycT1 (sc-10750)(Western blot,Immunoprecipitation) | H0807 | GeneCard:CCNT1 | CycT1 (sc-10750) | |
| CCNT2 | Goat polyclonal. Raised against an internal region of human CycT2a/b. Antibody Target: CCNT2 | CCNT2 | CycT2 is one of three cyclins that can form a heterodimer with cyclin-dependent kinase 9 (CDK9). The heterodimer is known as positive elongation factor b (P-TEFb) and is responsible for the phosphophorylation of Ser2 of the heptad repeat in the C-terminal domain of RNA polymerase II as well as the negative elongation factors DSIF (hSpt4/hSpt5) and NELF. Phosphorylation of RNA polymerase II and the negative elongation factors by P-TEFb promotes elongation. CycT2 contains a leucine rich domain capable of binding to the C-terminal domain of RNA polymerase II. | Santa Cruz Biotechnology sc-12419 | Struhl | Human - missing | H2306 | GeneCard:CCNT2 | CCNT2 (sc-12419) | |
| CDK9_(ab75898) | Rabbit polyclonal A/G affinity purified, immunogen= multiple synthetic peptides corresponding to C-terminal and N-terminal domains of the protein coded by the human gene cdk9 (PITALRE). Antibody Target: CDK9 | CDK9 | Cyclin dependent kinase 9 (CDK9) heterodimerizes with Cyclin T1 or Cyclin T2. The heterodimer is also known as positive elongation factor B (P-TEFb) and is responsible for the phosphorylation of Ser2 of the RNA polymerase II C-terminal | abcam ab75898 | Struhl | Human - CDK9 (ab75898)(Western blot,ChIP-seq) | GeneCard:CDK9 | CDK9 (ab75898) | ||
| CEBPB | Rabbit polyclonal IgG, epitope mapping at the C-terminus of CEBPB of rat origin. Antibody Target: CEBPB | CEBPB | Epitope mapping at the C-terminus of C/EBP-beta of rat origin | Santa Cruz Biotechnology sc-150 | Snyder, Myers | Human - CEBPB (sc-150)(Western blot,IP-MassSpec)
Human - CEBPB(sc-150)(Immunoprecipitation,Motif Enrichment) Mouse - missing |
I1010 | GeneCard:CEBPB | CEBPB (sc-150) | |
| CEBPB_(SC-150) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of CEBPB of rat origin. Antibody Target: CEBPB | CEBPB | Epitope mapping at the C-terminus of C/EBP-beta of rat origin | Santa Cruz Biotechnology sc-150 | Snyder,Myers | Human - CEBPB (sc-150)(Western blot,IP-MassSpec)
Human - CEBPB(sc-150)(Immunoprecipitation,Motif Enrichment) Mouse - missing |
I1010 | GeneCard:CEBPB | CEBPB (sc-150) | |
| CEBPD_(SC-636) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of CEBPD of human origin. Antibody Target: CEBPD | CEBPD | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11 (provided by RefSeq). | Santa Cruz Biotechnology sc-636 | Myers | Human - CEBPD (sc-636)(Western blot,IP-MassSpec) | C1010 | GeneCard:CEBPD | CEBPD (sc-636) | |
| CEBPZ | Rabbit polyclonal affinity purified, immunogen sequence= KDNASLKQLRWEAERDDWLHNRDAKSIIKKKKHFKKKRIKTTQKTKKQRK. Antibody Target: CEBPZ | CEBPZ | Stimulates transcription from the HSP70 promoter. | Sigma-Aldrich SAB2100398 | Snyder | Human - CEBPZ(Immunoprecipitation,IP-MassSpec) | QC8343 | GeneCard:CEBPZ | CEBPZ (SAB2100398) | |
| CELF1 | Mouse monoclonal. Raised against full-length GST fusion protein corresponding to human CUG-BP1, also known as heterogeneous nuclear ribonucleoprotein (hnRNP) hNab50. Antibody Target: CELF1 | CELF1 | Embryo deadenylation element-binding protein homolog (Homo sapiens) | Millipore 05-621 | Tenenbaum | Human - CELF1 (05-621)(Western blot,Immunoprecipitation) | GeneCard:CELF1 | CELF1 (05-621) | ||
| CHD1_(A301-218A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1 | CHD1 | CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337. | Bethyl Laboratories A301-218A | Bernstein | Human - CHD1 (A301-218A)(ChIP-String,ChIP-seq) | A301-218A-1 | GeneCard:CHD1 | CHD1 (A301-218A) | |
| CHD1_(NB100-60411) | Rabbit polyclonal affinity purified, The epitope recognized by this antibody maps to a region between residue 1660 and 1710 of human chromodomain helicase DNA binding protein 1 using the numbering given in entry NP_001261.2 (GeneID 1105). Antibody Target: CHD1 | CHD1 | ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells | Novus Biologicals NB100-60411 | Snyder | Human - CHD1 (NB100-60411)(Immunoprecipitation,IP-MassSpec)
Mouse - CHD1 (NB100-60411)(Immunoprecipitation,ChIP-seq) |
A1 | GeneCard:CHD1 | CHD1 (NB100-60411) | |
| CHD2_(AB68301) | Rabbit polyclonal to CHD2 Synthetic peptide derived from within residues 1250 - 1350 of Human CHD2. Antibody Target: CHD2 | CHD2 | CHD family of proteins are characterized by presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. | abcam ab68301 | Snyder | Human - missing
Mouse - missing |
GeneCard:CHD2 | CHD2 (ab68301) | ||
| CHD4_Mi2 | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Target: CHD4 | CHD4 | CHD4/Mi2beta is a helicase component of the nucleosome remodeling and deacetylase (NuRD) complex that functions to remodel chromatin and repress transcription. Outside of the NuRD complex, CHD4/Mi2beta can function as an activator of transcription in association with p300 histone acetyltransferase. | Bethyl Laboratories A301-081A | Bernstein | Human - CHD4 (A301-081A)(ChIP-seq,Western blot) | A301-081A-1 | GeneCard:CHD4 | CHD4/Mi2 (A301-081A) | |
| CHD7_(A301-223A-1) | Rabbit polyclonal antigen affinity purified, unconjugated, liquid. Antibody Target: CHD7 | CHD7 | CHD7 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. | Bethyl Laboratories A301-223A | Bernstein | Human - CHD7 (A301-223A)(ChIP-seq,Western blot) | A301-223A-1 | GeneCard:CHD7 | CHD7 (A301-223A) | |
| CREB1_(06-863) | Rabbit polyclonal A/G affinity purified, immunogen= KLH-conjugated, synthetic peptide (CSGAENQ QSGDAAVTEAENQQ) corresponding to a.a. 5-24 of human CREB. The immunizing sequence is identical in pig, shares 19 of 20 residues with mouse and bovine and 18 of 20 residues with rat. Antibody Target: CREB1 | CREB1 | CREB is a basic leucine zipper transcription factor. CREB is activated by phosphorylation of Ser133 in response to a range of stimuli by including a number of transcription factors PKA, CAMK and MAPKs. CREB is ubiquitously expressed, but has been specifically implicated in the development in neurite outgrowth and neuronal differentiation. | Millipore 06-863 | Struhl | Human - CREB1 (06-863)(Western blot,ChIP-seq) | GeneCard:CREB1 | CREB1 (06-863) | ||
| CREB1_(9198) | Rabbit monoclonal A/G affinity purified antibody produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser133 of human CREB. Antibody Target: CREB1 | CREB1 | CREB is a basic leucine zipper transcription factor. CREB is activated by phosphorylation of Ser133 in response to a range of stimuli by including a number of transcription factors PKA, CAMK and MAPKs. CREB is ubiquitously expressed, but has been specifically implicated in the development in neurite outgrowth and neuronal differentiation. | Cell Signaling Technology 9198 | Struhl | Human - CREB1 (9188) (Cell Signaling 9198)(Western blot,ChIP-seq) | GeneCard:CREB1 | CREB1 (9198) | ||
| CREB1_(SC-240) | Mouse monoclonal IgG1; raised against amino acids 254-327 mapping within the DNA binding and dimerization domain of human CREB-1. Antibody Target: CREB1 | CREB1 | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. (provided by RefSeq) | Santa Cruz Biotechnology sc-240 | Myers | Human - CREB1 (sc-240)(Western blot,IP-MassSpec) | C2306 | GeneCard:CREB1 | CREB1 (sc-240) | |
| CBP_(sc-369) | Rabbit polyclonal A/G affinity purified, epitope mapping at the N-terminus of CBP of human origin. Antibody Target: CREBB369P | CREBBP | CBP is a histone acetyl transferase that promotes transcription. CBP is recruited by a variety of transcription factors to promoters and enhancers. | Santa Cruz Biotechnology sc-369 | Struhl | Human - CBP (sc-369)(Western blot,ChIP-seq) | GeneCard:CREBBP | CBP (sc-369) | ||
| KAT3A_(ab2832) | Rabbit polyclonal affinity purified to a synthetic peptide, ATSSPATSQTGPGIC, corresponding to amino acids 162-176 in the nuclear factor binding domain of Human KAT3A / CBP. Antibody Target: CREBBP | CREBBP | Cyclic AMP-responsive enhancer binding protein (CREB) binding protein (CBP) and p300 are closely related transcriptional coactivators that have been shown to directly interact with many different DNA-binding transcription factors. Both CBP and p300 have been shown to display histone acetyltransferase (HAT) activity, capable of acetylating all four core histone particles in nucleosomes. | abcam ab2832 | Bernstein | Human - KAT3A (ab2832)(ChIP-seq,Western blot) | GeneCard:CREBBP | KAT3A (ab2832) | ||
| CtBP2 | Mouse monoclonal. Antibody Target: CTBP2 | CTBP2 | C-terminal binding protein 2 | BD Biosciences 612044 | Farnham | Human - CtBP2(Western blot,siRNA) | GeneCard:CTBP2 | CtBP2 (612044) | ||
| CTCF | Rabbit polyclonal. Antibody Target: CTCF | CTCF | CTCF zinc finger transcription factor. A sequence specific DNA binding protein that functions as an insulator, blocking enhancer activity. It has also been suggested to block the spreading of chromatin structure in certain instances. | Millipore 07-729 | Myers, Hardison, Snyder | Human - CTCF (07-729)(Western blot,Motif Enrichment)
Human - CTCF (07-729)(Western blot) Mouse - CTCF(Western blot) |
1350637 DAM1472197 | GeneCard:CTCF | CTCF (07-729) | |
| CTCF_(2899) | Rabbit polyclonal A/G affinity purified, detects endogenous levels of total CTCF protein and doesn't cross-react with BORIS. Antibody Target: CTCF | CTCF | CTCF is a ubiquitously expressed 11 zinc-finger protein that plays a central role in multiple complex processes, including transcription, imprinting, long-range chromatin interactions, subnuclear localization. CTCF has also been connected with multiple malignancies. | Cell Signaling Technology 2899 | Stam | Human - CTCF (2899)(Western blot) | 1 | GeneCard:CTCF | CTCF (2899) | |
| CTCF_(SC-15914) | Goat polyclonal, epitope mapping near the C-terminus of CTCF of human origin. Antibody Target: CTCF | CTCF | Transcriptional regulator with 11 highly conserved zinc finger domains. Depending on context, can bind a histone acetyltransferase (HAT)-containing complex and function as transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as transcriptional repressor. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation. Can dimerize, mediating long-range chromatin looping. When bound to chromatin, provides an anchor point for nucleosomes positioning. Involved in sister chromatid cohesion. Associates with both centromeres and chromosomal arms during metaphase and required for cohesin localization to CTCF sites. | Santa Cruz Biotechnology sc-15914 | Snyder | Human - missing
Mouse - missing |
GeneCard:CTCF | CTCF (sc-15914) | ||
| CTCF_(SC-5916) | Goat polyclonal IgG, epitope mapping at the N-terminus of CTCF of human origin. Antibody Target: CTCF | CTCF | This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. (provided by RefSeq) | Santa Cruz Biotechnology sc-5916 | Myers | Human - missing | K0902 | GeneCard:CTCF | CTCF (sc-5916) | |
| CTCFL_(SC-98982) | Rabbit polyclonal IgG, epitope corresponding to amino acids 91-210 mapping within an internal region of BORIS(CTCFL) of human origin. Antibody Target: CTCFL | CTCFL | CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. (provided by RefSeq) | Santa Cruz Biotechnology sc-98982 | Myers | Human - missing | E0109 | GeneCard:CTCFL | CTCFL (sc-98982) | |
| CDP_(sc-6327) | Goat polyclonal. CDP (C-20) is an affinity purified antibody raised against a peptide mapping at the C-terminus of CDP of mouse origin. Antibody Target: CUX1 | CUX1 | CDP (for CCAAT displacement protein) was identified as a repressor for tran- scription of developmentally regulated genes. It is a homeodomain protein that appears to compete with transcriptional activating proteins for binding to the promoter regions of various genes. CDP contains three cut repeats which function as DNA binding domains. It has been demonstrated that cut repeat domains have the capacity to bind to DNA in conjunction with or independently of homeodomain DNA binding. CDP has been shown to be the DNA-binding subunit of the HiNF-D complex, which contains cyclin A, Cdc2 and an Rb-related protein in addition to CDP. Histone expression is required for the transition to S phase in the cell cycle. The HiNF-D complex regulates the transcription of Histone H4, H3 and H1 genes, allowing cells to progress from G1 to S phase. | Santa Cruz Biotechnology sc-6327 | Snyder | Human - CDP (sc-6327)(Immunoprecipitation,IP-MassSpec) | E0709 | GeneCard:CUX1 | CDP (sc-6327) | |
| E2F1 | Mouse monoclonal. E2F1(KH20 and KH95) Epitope for KH20 has been mapped to amino acids 1-89; KH95 to amino acids 342-386. Antibody Target: E2F1 | E2F1 | E2F1, the original member of the E2F family of transcription factors, was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter. E2F1 is cell cycle regulated with very low levels in early G1, then increasing levels as cells move from G1 to S, and highest levels of protein at the G1/S boundary, which is consistent with its role in S-phase entry. | Millipore 05-379 | Farnham | Human - E2F1(Immunoprecipitation-Western blot,ChIP-seq) | GeneCard:E2F1 | E2F1 (05-379) | ||
| E2F4 | Rabbit polyclonal affinity purified. Antibody Target: E2F4 | E2F4 | mapping at the C-terminus of E2F4 of human origin | Santa Cruz Biotechnology sc-866 | Farnham, Snyder | Human - E2F4(sc-866)(Immunoprecipitation-Western blot,ChIP-seq)
Mouse - E2F4 (sc-866)(Immunoprecipitation,ChIP-seq) |
GeneCard:E2F4 | E2F4 (sc-866) | ||
| E2F6 | Rabbit polyclonal IgG, epitope corresponding to a.a. 232-281 mapping at the C-terminus of E2F-6 of human origin. Antibody Target: E2F6 | E2F6 | This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms (RefSeq). | Santa Cruz Biotechnology sc-22823 | Farnham, Myers | Human - E2F6(sc-22823)(Western blot,siRNA-ChIP)
Human - E2F6 (sc-22823)(Western blot,IP-MassSpec) |
D1206 (Myers) | GeneCard:E2F6 | E2F6 (sc-22823) | |
| EBF1_(SC-137065) | Mouse monoclonal IgG, raised against a.a. 1-300 mapping at the N-terminus of EBF of human origin. Antibody Target: EBF1 | EBF1 | Early B-cell factor 1. Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity). | Santa Cruz Biotechnology sc-137065 | Myers | Human - EBF1 (sc-137065)(Immunoprecipitation-Western blot,IP-MassSpec) | J0505 | GeneCard:EBF1 | EBF1 (sc-137065) | |
| eGFP-BACH1 | Goat polyclonal raised against e-GFP tagged transcription factor BACH1. Antibody Target: eGFP-BACH1 | eGFP-BACH1 | This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-BACH1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:BACH1 | BACH1 (eGFP-BACH1) | |
| eGFP-CCNE1 | Goat polyclonal raised against e-GFP tagged transcription factor CCNE1. Antibody Target: eGFP-CCNE1 | eGFP-CCNE1 | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-CCNE1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:CCNE1 | CCNE1 (eGFP-CCNE1) | |
| eGFP-CDKN1B | Goat polyclonal raised against e-GFP tagged transcription factor CDKN1B. Antibody Target: eGFP-CDKN1B | eGFP-CDKN1B | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1 (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-CDKN1B | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:CDKN1B | CDKN1B (eGFP-CDKN1B) | |
| eGFP-E2F1 | Goat polyclonal raised against e-GFP tagged transcription factor E2F1. Antibody Target: eGFP-E2F1 | eGFP-E2F1 | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-E2F1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:E2F1 | E2F1 (eGFP-E2F1) | |
| eGFP-ELF1 | Goat polyclonal raised against e-GFP tagged transcription factor ELF1. Antibody Target: eGFP-ELF1 | eGFP-ELF1 | This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-ELF1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:ELF1 | ELF1 (eGFP-ELF1) | |
| eGFP-ESR | Goat polyclonal raised against e-GFP tagged transcription factor ESRA. Antibody Target: eGFP-ESR | eGFP-ESR1 | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-ESR | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:ESR | ESR (eGFP-ESR) | |
| eGFP-FOS | Goat polyclonal. Antibody Target: eGFP-FOS | eGFP-FOS | FOS | Dr. Kevin White at University of Chicago Missing | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:FOS | FOS (eGFP-FOS) | ||
| eGFP-GATA2 | Goat polyclonal. Antibody Target: GATA2 | eGFP-GATA2 | GATA2 | Dr. Kevin White at University of Chicago eGFP-GATA2 | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:GATA2 | GATA2 (eGFP-GATA2) | ||
| eGFP-HDAC8 | Goat polyclonal. Antibody Target: eGFP-HDAC8 | eGFP-HDAC8 | HDAC8 | Dr. Kevin White at University of Chicago eGFP-HDAC8 | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:HDAC8 | HDAC8 (eGFP-HDAC8) | ||
| eGFP-HMGB1 | Goat polyclonal raised against e-GFP tagged transcription factor HMGB1. Antibody Target: eGFP-HMGB1 | eGFP-HMGB1 | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-HMGB1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:HMGB1 | HMGB1 (eGFP-HMGB1) | |
| eGFP-ILF2 | Goat polyclonal raised against e-GFP tagged transcription factor ILF2. Antibody Target: eGFP-ILF2 | eGFP-ILF2 | Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-ILF2 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:ILF2 | ILF2 (eGFP-ILF2) | |
| eGFP-JunB | Goat polyclonal. Antibody Target: JUNB | eGFP-JUNB | JUNB | Dr. Kevin White at University of Chicago eGFP-JUNB | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:JUNB | JUNB (eGFP-JunB) | ||
| eGFP-JunD | Goat polyclonal. Antibody Target: JUND | eGFP-JUND | JUND | Dr. Kevin White at University of Chicago eGFP-JUND | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:JUND | JUND (eGFP-JUND) | ||
| eGFP-MLL5 | Goat polyclonal raised against e-GFP tagged transcription factor MLL5. Antibody Target: eGFP-MLL5 | eGFP-MLL5 | This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-MLL5 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:MLL5 | MLL5 (eGFP-MLL5) | |
| eGFP-NCOR1 | Goat polyclonal raised against e-GFP tagged transcription factor NCOR1. Antibody Target: eGFP-NCOR1 | eGFP-NCOR1 | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17 (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-NCOR1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:NCOR1 | NCOR1 (eGFP-NCOR1) | |
| eGFP-NF90 | Goat polyclonal raised against e-GFP tagged transcription factor NF90. Antibody Target: eGFP-NF90 | eGFP-NF90 | NF90 (nuclear factor of activated T cells 90 kDa), also known as NFAR is a ubiquitously expressed nuclear protein that exists in a heterodimer with NF45. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-NF90 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:ILF3 | NF90 (eGFP-NF90) | |
| eGFP-NR4A1 | Goat polyclonal. Antibody Target: NR4A1 | eGFP-NR4A1 | NR4A1 | Dr. Kevin White at University of Chicago eGFP-NR4A1 | White | Human - eGFP(Western blot,Immunoprecipitation) | GeneCard:NR4A1 | NR4A1 (eGFP-NR4A1) | ||
| eGFP-SMARCA1 | Goat polyclonal raised against e-GFP tagged transcription factor SMARCA1. Antibody Target: eGFP-SMARCA1 | eGFP-SMARCA1 | This gene encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-SMARCA1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:SMARCA1 | SMARCA1 (eGFP-SMARCA1) | |
| eGFP-SMARCA2 | Goat polyclonal raised against e-GFP tagged transcription factor SMARCA2. Antibody Target: eGFP-SMARCA2 | eGFP-SMARCA2 | The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-SMARCA2 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:SMARCA2 | SMARCA2 (eGFP-SMARCA2) | |
| eGFP-STAT1 | Goat polyclonal raised against e-GFP tagged transcription factor STAT1. Antibody Target: eGFP-STAT1 | eGFP-STAT1 | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6 (provided by RefSeq) | Dr. Kevin White at University of Chicago eGFP-STAT1 | White | Human - eGFP(Western blot,Immunoprecipitation) | 1 | GeneCard:STAT1 | STAT1 (eGFP-STAT1) | |
| Egr-1 | Rabbit polyclonal, EGR-1 (588). Antibody Target: EGR1 | EGR1 | Egr-1, Egr-2, Egr-3 and Egr-4 are nuclear transcription factors belonging to the Egr C2H2-type zinc-finger protein family and containing three C2H2-type zinc fingers. As immediate early proteins, Egr transcription factors are rapidly induced by diverse extracellular stimuli. Egr proteins are subject to tight differential control through diverse mechanisms at several levels of regulation including transcriptional, translational and post-translational (including glyco- sylation, phosphorylation and redox) mechanisms and protein-protein inter- action. Egr-1 binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site), there- by activating transcription of target genes whose products are required for mitogenisis and differentiation. Egr-2 binds specific DNA sites located in the promoter region of HoxA4. Egr-2 defects cause congenital hypomyelination neuropathy (also designated Charcot-Marie-tooth disease) and Dejerine- Sottas neuropathology (also designated hereditary motor and sensory neuro- pathy III. Egr-3 is involved in muscle spindle development and is expressed in T cells 20 minutes following activation. EGR-4 binds to the EGR consensus motif GCGTGGGCG, functions as a transcriptional repressor, and displays autoregulatory activities, downregulating its on gene promoter in a dose dependent manner. | Santa Cruz Biotechnology sc-110 | Farnham,Myers | Human - Egr-1(sc-110)(Immunoblot) | GeneCard:EGR1 | EGR1 (sc-110) | ||
| ELAVL1 | Mouse monoclonal vs HuR, Hel-N1, HuC and HuD of mus, rat, hum and Xenopus origin; 2) Rabbit polyclonal. Raised against synthetic peptide, amino acids 3-19 of HuR. Recommended for detection against ELAV1 in human and mouse origin. Antibody Target: ELAVL1 | ELAVL1 | (Embryonic lethal, abnormal vision, Drosophila)-like 1 (Huantigen R) (Homo sapiens) | 1) Santa Cruz Biotechnology sc-5261 2) Millipore 07-1735 |
Tenenbaum | Human - ELAVL1 (sc-5261)(Western blot,Immunoprecipitation)
Human - ELAVL1 (07-1735)(Western blot,Immunoprecipitation) |
B2508 | GeneCard:ELAVL1 | ELAVL1 (sc-5261; 07-1735) | |
| ELF1_(SC-631) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of Elf-1 of human origin. Antibody Target: ELF1 | ELF1 | This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. (provided by RefSeq) | Santa Cruz Biotechnology sc-631 | Myers | Human - ELF1 (sc-631)(Western blot,IP-MassSpec) | L2707 | GeneCard:ELF1 | ELF1 (sc-631) | |
| ELK1_(1277-1) | Rabbit polyclonal affinity purified, a synthetic peptide corresponding to residues in C-terminus of human ELK-1 was used as immunogen. The antibody does not cross-react with other ETS family members. Antibody Target: ELK1 | ELK1 | Elk-1 is a transcription factor that is part of the ets oncogene superfamily. Elk-1 forms a ternary complex with the serum response factors, SRE and SRF, mediating gene activity in response to serum and growth factors. Activation by several mitogen- activated protein kinases (Erk1 and Erk2) mediates the immediate early responses of the c-fos promoter to growth factors and other stimuli. | Epitomics 1277-1 | Snyder | Human - ELK1(1277-1)(Immunoprecipitation,IP-MassSpec) | YG030402C | GeneCard:ELK1 | ELK1 (1277-1) | |
| ELK4 | Rabbit polyclonal IgG affinity purified. Antibody Target: ELK4 | ELK4 | This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. (provided by RefSeq) | Santa Cruz Biotechnology sc-13030 | Farnham | Human - ELK4(Western blot,ChIP-seq) | E0603 | GeneCard:ELK4 | ELK4 (sc-13030) | |
| p300 | Rabbit polyclonal. Antibody Target: EP300 | EP300 | EP300(c-20) | Santa Cruz Biotechnology sc-585 | Myers, Ren | Human - P300(sc-585)(Western blot)
Mouse - P300(SC-585)(Western blot,ChIP-seq) |
D0411 E2209 | GeneCard:EP300 | P300/EP300 (sc-585) | |
| p300_(SC-48343) | Mouse monoclonal raised against amino acids 774-1045 of p300 of human origin. Antibody Target: EP300 | EP300 | Encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. | Santa Cruz Biotechnology sc-48343 | Snyder | Human - missing | GeneCard:EP300 | P300/EP300 (sc-48343) | ||
| p300_(SC-584) | Rabbit polyclonal IgG, epitope mapping at the N-terminus of p300 of human origin. Antibody Target: EP300 | EP300 | Encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. Functions as histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein | Santa Cruz Biotechnology sc-584 | Snyder | Human - missing
Mouse - missing |
GeneCard:EP300 | P300/EP300 (sc-584) | ||
| P300_KAT3B | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: EP300 | EP300 | Histone acetyltransferase with sequence similarity to CBP (CREB-binding protein). Regulates transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. | Bethyl Laboratories A300-358A | Bernstein | Human - P300 (A300-358A)(ChIP-seq,Western blot) | A300-358A-1 | GeneCard:EP300 | P300/EP300/KAT3B (A300-358A) | |
| ERalpha_a | Rabbit polyclonal affinity purified antibody. Epitope is the C-terminus of human estrogen receptor alpha (ESR1). Antibody Target: ESR1 | ESR1 | This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq) | Santa Cruz Biotechnology sc-543 | Ruan, Myers | Human - ERalpha a(Immunoprecipitation-Western blot,IP-MassSpec) | C2510 G1509 | GeneCard:ESR1 | ERalpha a (sc-543) | |
| ERRA | Rabbit polyclonal IgG, epitope mapping at the C-terminus of Ets-1 of human origin. Antibody Target: ESRRA | ESRRA | Epitope corresponding to amino acids 81-160 mapping near the N-terminus of ERRalpha of human origin | Santa Cruz Biotechnology sc-66882 | Snyder | Human - ERRA(Western blot,Motif Enrichment) | A0809 | GeneCard:ESRRA | ESRRA (sc-66882) | |
| ETS1 | Rabbit polyclonal IgG. Antibody Target: ETS1 | ETS1 | ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis | Santa Cruz Biotechnology sc-350 | Myers | Human - ETS1(Immunoprecipitation-Western blot,IP-MassSpec)
Mouse - missing |
A1608 | GeneCard:ETS1 | ETS1 (sc-350) | |
| EZH2_(39875) | Mouse monoclonal A/G affinity purified raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2 | EZH2 | EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers. | Active Motif 39875 | Bernstein | Human - EZH2 (39875)(Western blot,ChIP-seq) | 27210001 | GeneCard:EZH2 | EZH2 (39875) | |
| SPT20 | Rabbit polyclonal anti-SPT20 antibody (3006), Immunogen: C-terminal region of mSPT20 (330-531 aa) is cloned in pET28b and over expressed in E. Coli. Protein was purified on Ni-NTA exchange column. Sequence: mSPT20 (330-531 amino acids). Antibody Target: FAM48A | FAM48A | Also known as FAM48A or P38IP. It is a component of SAGA complex. Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. | Dr. Lazlo Tora at Institut de Gènètique et de Biologie Molèculaire et Cellulaire SPT20 (3006) | Struhl | Human - missing | GeneCard:FAM48A | SPT20/FAM48A (3006) | ||
| FLI1_(sc-356) | Rabbit polyclonal. FLI1 (C-19) is an affinity purified antibody raised against a peptide mapping at the C-terminus of FLI1 of mouse origin. Antibody Target: FLI1 | FLI1 | Fli1 (Friend leukemia virus integration 1) is a member of a family of genes identified on the basis of their homology to the v-Ets oncogene isolated from the E26 erythoblastosis virus. | Santa Cruz Biotechnology sc-356 | Hardison | Mouse - FLI1 (sc-356)(Western blot,Correlation) | E1211 | GeneCard:FLI1 | FLI1 (sc-356) | |
| c-Fos | Rabbit polyclonal affinity purified to amino acids 210-335 mapping at the C-terminus of c-Fos of human origin. Antibody Target: FOS | FOS | Heterodimer of Fos and Jun constitute transcription factor AP1. Proto-oncogene c-Jun is a leucine-zipper. | Santa Cruz Biotechnology sc-7202 | Snyder | Human - c-Fos (sc-7202)(Immunoprecipitation,Motif Enrichment) | K0810 | GeneCard:FOS | c-Fos (sc-7202) | |
| FOSL1_(SC-183) | Rabbit polyclonal IgG, epitope mapping at the N-terminus of FOSL1 of human origin. Antibody Target: FOSL1 | FOSL1 | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (provided by RefSeq) | Santa Cruz Biotechnology sc-183 | Myers | Human - FOSL1 (sc-183)(Western blot,IP-MassSpec) | I0809 | GeneCard:FOSL1 | FOSL1 (sc-183) | |
| FOSL1_(sc-605) | Rabbit polyclonal antibody raised against the N-terminus of FOSL1 of rat origin. Antibody Target: FOSL1 | FOSL1 | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (provided by RefSeq) | Santa Cruz Biotechnology sc-605 | Wold | Mouse - missing | G0109 | GeneCard:FOSL1 | FOSL1 (sc-605) | |
| FOSL2 | Rabbit polyclonal. Fra-2(Q-20) is an affinity purified raised against the N-terminus of Fra-2 of human origin. Antibody Target: FOSL2 | FOSL2 | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. | Santa Cruz Biotechnology sc-604 | Myers | Human - FOSL2(Immunoblot) | GeneCard:FOSL2 | FOSL2 (sc-604) | ||
| FOXA1_(SC-101058) | Mouse monoclonal IgG, raised against recombinant HNF-3a of human origin. Antibody Target: FOXA1 | FOXA1 | This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. (provided by RefSeq) | Santa Cruz Biotechnology sc-101058 | Myers | Human - FOXA1 (sc-101058)(Immunoprecipitation-Western blot,IP-MassSpec) | A2706 | GeneCard:FOXA1 | FOXA1 (sc-101058) | |
| FOXA1_(SC-6553) | Goat polyclonal IgG, epitope mapping at the C-terminus of FOXA1 of human origin. Antibody Target: FOXA1 | FOXA1 | This gene encodes a member of the forehead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver (RefSeq). | Santa Cruz Biotechnology sc-6553 | Myers | Human - FOXA1(Immunoprecipitation-Western blot,IP-MassSpec) | H1209 | GeneCard:FOXA1 | FOXA1 (sc-6553) | |
| FOXA2_(SC-6554) | Goat polyclonal IgG, epitope mapping at the N-terminus of FOXA2 of human origin. Antibody Target: FOXA2 | FOXA2 | The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. (provided by RefSeq) | Santa Cruz Biotechnology sc-6554 | Myers | Human - missing | L1409 | GeneCard:FOXA2 | FOXA2 (sc-6554) | |
| FOXM1_(SC-502) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of FOXM1 of human origin. Antibody Target: FOXM1 | FOXM1 | The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2011) | Santa Cruz Biotechnology sc-502 | Myers | Human - FOXM1 (sc-502)(Western blot,IP-MassSpec) | C1909 | GeneCard:FOXM1 | FOXM1 (sc-502) | |
| FOXP2 | Rabbit polyclonal, raised against C-terminal 127 amino acids of FOXP2 of human origin. Antibody Target: FOXP2 | FOXP2 | This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. Transcriptional repressor, involved in the development of speech | abcam ab16046 | Myers | Human - FOXP2(Western blot,siRNA) | AB-2B | GeneCard:FOXP2 | FOXP2 (ab16046) | |
| GABP | Mouse monoclonal, GABPa(G-1), IgG1. Antibody Target: GABP | GABPA | The transcription factor GA-binding protein (GABP) is composed of two subunits, alpha and beta. Alpha binds to a specific DNA sequence. | Santa Cruz Biotechnology sc-28312 | Myers | Human - GABP(Immunoprecipitation-Western blot,IP-MassSpec) | F1804 | GeneCard:GABPA | GABPA (sc-28312) | |
| Nrf2 | Rabbit polyclonal IgG. Epitope corresponding to amino acids 1-180 mapping at the N-terminus of GABP-α of human origi. Antibody Target: GABPA | GABPA | Epitope corresponding to amino acids 1-180 mapping at the N-terminus of GABP-α of human origin | Santa Cruz Biotechnology sc-22810 | Snyder | Mouse - missing | GeneCard:GABPA | Nrf2 (sc-22810) | ||
| GATA-1 | Rabbit polyclonal antibody generated using a purified GST fusion to amino acids 1-89 of mouse GATA-1. Antibody Target: GATA1 | GATA1 | GATA-1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG} within regulatory regions of globin genes and of other genes expressed in erythroid cells. | Dr. E.H. Bresnick at UW Madison GATA-1 | Farnham | Human - GATA-1 (Western blot,ChIP-seq)
Mouse - missing |
GeneCard:GATA1 | GATA1 | ||
| GATA1_(SC-265) | Rat monoclonal antibody raised against mouse recombinant GATA1; recommended for detection of GATA1 of mouse, rat and human origin. Antibody Target: GATA1 | GATA1 | GATA1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. | Santa Cruz Biotechnology sc-265 | Hardison | Mouse - GATA1(Western blot) | GeneCard:GATA1 | GATA1 (sc-265) | ||
| GATA1_(SC-266) | Rat monoclonal raised against bacterially expressed murine GATA-1. Antibody Target: GATA1 | GATA1 | GATA1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. | Santa Cruz Biotechnology sc-266 | Snyder | Human - GATA1 (sc-266)(Immunoprecipitation,Motif Enrichment)
Mouse - GATA1(sc-266)(Immunoprecipitation) Mouse - GATA1 (sc-266)(Immunoprecipitation,Motif Enrichment) |
B2510 | GeneCard:GATA1 | GATA1 (sc-266) | |
| GATA-2 | Rabbit polyclonal. Antibody Target: GATA2 | GATA2 | GATA binding protein 2 | Dr. E.H. Bresnick at UW Madison GATA-2 | Farnham | Human - GATA-2(Western blot,siRNA) | GeneCard:GATA2 | GATA2 | ||
| GATA2_(SC-267) | Mouse monoclonal IgG. Antibody Target: GATA2 | GATA2 | This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded program plays an essential role in regulation transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages (RefSeq). | Santa Cruz Biotechnology sc-267 | Myers | Human - GATA2 (sc-267)(Immunoprecipitation-Western blot,IP-MassSpec) | E2708 | GeneCard:GATA2 | GATA2 (sc-267) | |
| GATA2_(SC-9008) | Rabbit polyclonal antibody raised against amino acids 120-235 of GATA-2 of human origin. Antibody Target: GATA2 | GATA2 | The GATA family of transcription factors share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA1 is erythroid-specific and is essential for normal erythropeisis. By comparison, GATA2 is expressed at high levels in hematopoeitic progenitors, including early erythroid cells, but is strong repressed during erythroblast differentiaion. | Santa Cruz Biotechnology sc-9008 | Hardison | Mouse - GATA2 (sc-9008)(Western blot) | J2108 | GeneCard:GATA2 | GATA2 (sc-9008) | |
| GATA3_(SC-268) | Mouse monoclonal IgG raised against human recombinant GATA-3. Antibody Target: GATA3 | GATA3 | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is a n important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (provided by RefSeq). | Santa Cruz Biotechnology sc-268 | Farnham | Human - GATA3 SC-268(Western blot,ChIP-seq) | G0910 | GeneCard:GATA3 | GATA3 (sc-268) | |
| GATA3_(SC-269) | Mouse monoclonal IgG affnity purified, raised against human recombinant GATA-3 (amino acids 1-264). Antibody Target: GATA3 | GATA3 | This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is a n important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (provided by RefSeq) | Santa Cruz Biotechnology sc-269 | Farnham | Human - GATA3 SC-269 (siRNA,ChIP-seq) | A1404 | GeneCard:GATA3 | GATA3 (sc-269) | |
| GRp20 | Rabbit polyclonal IgG affinity purified. Antibody Target: GRp20 | GRp20 | Epitope mapping at the C-terminus of GR alpha of human origin | Santa Cruz Biotechnology sc-1002 | Snyder | Human - GRp20 (sc-1002)(Western blot,IP-MassSpec) | GeneCard:NR3C1 | GRp20 (sc-1002) | ||
| GTF2B | Rabbit polyclonal A/G affinity purified. Raised against an epitope mapping to C-terminus of human TFIIB. Recommended for detection of TFIIB p33 of mouse, rabbit and human origin. Antibody Target: GTF2B | GTF2B | DNA- binding general transcription factor | Santa Cruz Biotechnology sc-225 | Struhl | Human - TFIIB (sc-225)(Western blot,ChIP-seq) | J1905 | GeneCard:GTF2B | GTF2B (sc-225) | |
| GTF2F1_(AB28179) | Rabbit polyclonal to TFIIF - Recombinant full length protein - RAP 74 subunit of TF11F. Antibody Target: GTF2F1 | GTF2F1 | RNA polymerase II transcription factor TFIIF is a heterodimer with 2 subunits: one, referred to as RAP74. TFIIF appears to assist TFIIB in recruiting RNA polymerase II into a preinitiation complex. It also affects RNA transcription by suppressing transient pausing of the polymerase at locations on the DNA template. | abcam ab28179 | Snyder | Human - GTF2F1 (AB28179)(Western blot,Immunoprecipitation) | GeneCard:GTF2F1 | GTF2F1 (ab28179) | ||
| TFIIIC-110 | Rabbit polyclonal. Antiserum 4286 was raised by immunizing rabbits with synthetic peptide RPGFSPTSHRLLPTP (human TFIIIC110 residues 897 to 911) coupled to keyhole limpet hemocyanin. Antibody Target: GTF3C2 | GTF3C2 | TFIIIC-110 is a subunit of the RNA Polymerase III transcription factor TFIIIC. | Dr. Robert J. White at Beatson Institute for Cancer Research TFIIIC-110 4286 | Struhl | Human - TFIIIC-110(4286)(IP-MassSpec,Correlation) | GeneCard:GTF3C2 | TFIIIC-110 (4286) | ||
| H2A.Z | Rabbit polyclonal antibody A/G affinity purified, raised against a peptide corresponding to the C-terminus of H2A.Z. Antibody Target: H2AFZ | H2AFZ | H2A.Z (H2AFZ) is a sequence variant of Histone H2A. | Millipore 07-594 | Bernstein | Human - H2A.Z (07-594)(Western blot,ChIP-seq) | DAM1540736 | GeneCard:H2AFZ | H2AZ (07-594) | |
| H3ac_(06-599) | Rabbit polyclonal antibody raised against a KLH-conjugated peptide corresponding to amino acids 1-20 of Tetrahymena histone H3 (ARTKQTAR[K*]STGG[K*]APRKQLC) where K* is acetylated. Antibody Target: H3ac | H3ac | missing | Millipore 06-599 | Wold | Mouse - missing | GeneCard:HIST2H3C | H3ac (06-599) | ||
| H3K27ac | Rabbit polyclonal. Antibody Target: H3K27ac | H3K27ac | Histone H3 (acetyl K27). As with H3K9ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation has can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases. | abcam ab4729 | Bernstein | Human - H3K27ac(Dot blot) | 31456 | GeneCard:HIST2H3C | H3K27ac (ab4729) | |
| H3K27Ac_(39133) | Rabbit polyclonal to Histone H3 K27 acetylation | H3K27ac | Specific for detecting Histone H3 K27 acetylation only | Active Motif 39133 | Ren | Mouse - H3K27Ac (39133)(Dot blot,Western blot) | 19208002 | GeneCard:HIST2H3C | H3K27Ac_(39133) | |
| H3K27me3 | Rabbit polyclonal. Antibody Target: H3K27me3 | H3K27me3 | Histone H3 (tri-methyl K27). Marks promoters that are silenced by Polycomb proteins in a given lineage; large domains are found at inactive developmental loci. | Millipore 07-449 | Bernstein, Hardison | Human - H3K27me3(Dot blot)
Mouse - H3K27me3 (07-449)(Dot blot) |
DAM1387952 | GeneCard:HIST2H3C | H3K27me3 (07-449) | |
| H3K27me3_(39155) | Rabbit polyclonal to Histone H3 K27 trimethylation | H3K27me3 | This antibody only detects Histone H3 trimethylated on Lysine 27 | Active Motif 39155 | Ren | Mouse - H3K27me3 (39155)(Dot blot,Western blot) | 30508004 | GeneCard:HIST2H3C | H3K27me3_(39155) | |
| H3K27me3B | Rabbit monoclonal. Antibody Target: H3K27me3 | H3K27me3 | Histone H3 (tri-methyl K27) marks repressed chromatin regions | Cell Signaling Technology 9733S | Farnham | Human - H3K27me3B(Western blot,Peptide ELISA) | 1 | GeneCard:HIST2H3C | H3K27me3 (9733S) | |
| H3K36me3 | Rabbit polyclonal. Antibody Target: H3K36me3 | H3K36me3 | Specific for histone H3 tri methylated at lysine 36, weakly reacts with H3K36me2. Marks regions of RNAPII elongation, including coding and non-coding transcripts. | abcam ab9050 | Bernstein, Ren, Hardison | Human - H3K36me3(ab9050)(Dot blot)
Mouse - H3K36me3 (ab9050)(Dot blot,Western blot) Mouse - H3K36me3 (ab9050)(Dot blot) |
136353 707946 499302 947454 826245 | GeneCard:HIST2H3C | H3K36me3 (ab9050) | |
| H3K36me3B | Rabbit polyclonal. Antibody Target: H3K36me3 | H3K36me3 | Histone H3 (tri-methyl K36) marks actively transcribed chromatin regions | Cell Signaling Technology 9763S | Farnham | Human - H3K36me3B(Western blot,Peptide ELISA) | GeneCard:HIST2H3C | H3K36me3 (9763S) | ||
| H3K4me1 | Rabbit polyclonal affinity purified. Antibody Target: H3K4me1 | H3K4me1 | Histone H3 (mono methyl K4). Is associated with enhancers, and downstream of transcription starts. | abcam ab8895 | Bernstein, Ren, Hardison | Human - H3K4me1(ab8895)(Dot blot)
Mouse - H3K4me1(ab8895)(Dot blot,Western blot) Mouse - H3K4me1(ab8895)(Dot blot) |
383111 720417 | GeneCard:HIST2H3C | H3K4me1 (ab8895) | |
| H3K4me1_(pAb-037-050) | Rabbit polyclonal affinity purified antibody raised against histone H3 containing the monomethylated lysine 4 (H3K4me1), using a KLH-conjugated synthetic peptide. Antibody Target: H3K4me1 | H3K4me1 | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution.Histone tails undergo numerous posttranslational modifications. This antibodies recognizes histone H3 monomethylated on lysine 4. | Diagenode pAb-037-050 | Farnham | Human - H3K4me1 (pAb-037-050)(Western blot,Dot blot) | A399-002341P | GeneCard:HIST2H3C | H3K4me1 (pAb-037-050) | |
| H3K4me2 | Rabbit polyclonal. Antibody Target: H3K4me2 | H3K4me2 | Histone H3 (di methyl K4). Marks promoters and enhancers. Most CpG islands are marked by H3K4me2 in primary cells. May be associated also with poised promoters. | abcam ab7766 | Bernstein | Human - H3K4me2(Dot blot) | 56293 | GeneCard:HIST2H3C | H3K4me2 (ab7766) | |
| H3K4me2_(ab32356) | Rabbit monoclonal [Y47] to Histone H3 (di methyl K4) - ChIP Grade. Antibody Target: H3K4me2 | H3K4me2 | Histone H3 dimethylated on Lysine 4. Marks promoters and enhancers. | abcam ab32356 | Wold, Ren | Mouse - H3K4me2 (ab32356)(Dot blot,Western blot) | 870402 577702 | GeneCard:HIST2H3C | H3K4me2 (ab32356) | |
| H3K4me3 | Rabbit polyclonal. Antibody Target: H3K4me3 | H3K4me3 | Histone H3 (tri methyl K4). Marks promoters that are active or poised to be activated. | 1)abcam ab8580 2)Millipore 07-473 |
Bernstein, Hardison | Human - H3K4me3(Dot blot)
Mouse - H3K4me3 (ab8580)(Dot blot) Mouse - H3K4me3 (07-473)(Dot blot) |
498616 331024(ab8580) R0903B0054(07-473) | GeneCard:HIST2H3C | H3K4me3 (07-473) | |
| H3K4me3_(04-745) | Rabbit monoclonal anti-trimethyl-Histone H3 (Lys4) Antibody, clone MC315 | H3K4me3 | Detect only histone H3 containing trimethyl-lysine 4 | Millipore 04-745 | Ren | Mouse - H3K4me3 (04-745)(Dot blot,Western blot) | NG1643014 | GeneCard:HIST2H3C | H3K4me3 (04-745) | |
| H3K4me3B | Rabbit monoclonal antibody. Antibody Target: H3K4me3 | H3K4me3 | Histone H3 (tri-methyl K4) marks promoters in chromatin regions | Cell Signaling Technology 9751S | Farnham | Human - H3K4me3B(Western blot,Competitor peptides) | 1 2 | GeneCard:HIST2H3C | H3K4me3 (9751S) | |
| H3K79me2 | Rabbit polyclonal antibody raised against a peptide containing K79 di-methylation. Antibody Target: H3K79me2 | H3K79me2 | H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3). | Active Motif 39143 | Bernstein, Ren | Human - H3K79me2(Dot blot)
Mouse - H3K79me2 (39143)(Dot blot,Western blot) |
177/0100800 | GeneCard:HIST2H3C | H3K79me2 (39143) | |
| H3K79me2_(ab3594) | Rabbit polyclonal. Antibody Target: H3K79me2 | H3K79me2 | H3K79me2 is a mark of the transcriptional transition region - the region between the initiation marks (K4me3, etc) and the elongation marks (K36me3) | abcam ab3594 | Wold | Mouse - missing | 836403 | GeneCard:HIST2H3C | H3K79me2 (ab3594) | |
| H3K79me3_(ab2621) | Rabbit polyclonal. Antibody Target: H3K79me3 | H3K79me3 | Associated with the gene body of actively transcribed genes | abcam ab2621 | Wold | Mouse - missing | 805949 | GeneCard:HIST2H3C | H3K79me3 (ab2621) | |
| H3K9ac | Rabbit polyclonal A/G affinity purified. Antibody Target: H3K9ac | H3K9ac | Histone H3 (acetyl K9). As with H3K27ac, associated with transcriptional initiation and open chromatin structure. It remains unknown whether acetylation can have different consequences depending on the specific lysine residue targeted. In general, though, there appears to be high redundancy. Histone acetylation is notable for susceptibility to small molecules and drugs that target histone deacetylases. | abcam ab4441 | Bernstein | Human - H3K9ac (ab4441)(Western blot,ChIP-seq) | 455103 550799 | GeneCard:HIST2H3C | H3K9ac (ab4441) | |
| H3K9Ac_(39137) | Rabbit polyclonal to Histone H3 K9 acetylation | H3K9ac | Detect only Histone H3 K9 acetylation | Active Motif 39137 | Ren | Mouse - H3K9Ac (39137)(Dot blot,Western blot) | 1008001 | GeneCard:HIST2H3C | H3K9Ac_(39137) | |
| H3K9Ac_(9649) | Rabbit monoclonal antibody corrresponds to the amino terminus of acetyl-histone H3 (Lys9), this antibody does not cross-react with other acetylated histones. Antibody Target: H3K9ac | H3K9ac | H3K9ac, acetyl-histone H3 (Lys9) | Cell Signaling Technology 9649 | Farnham | Human - H3K9Ac (9649)(Western blot,Dot blot) | 1 | GeneCard:HIST2H3C | H3K9ac (9649) | |
| H3K9acB | Rabbit polyclonal. Antibody Target: H3K9ac | H3K9ac | Histone H3 (acetyl K9) marks promoters in chromatin regions | Millipore 07-352 | Farnham | Human - H3K9Ac (07-352)(Western blot,ChIP-seq) | GeneCard:HIST2H3C | H3K9ac (07-352) | ||
| H3K9me3 | Rabbit polyclonal affinity purified, ChIP grade. Antibody Target: H3K9me3 | H3K9me3 | Histone H3 (tri methyl K9). Is associated with repressive heterochromatic state (silenced chromatin). NOTE CONTRAST to H3K9me1 which is associated with active and accessible regions. | abcam ab8898 | Farnham, Ren, Hardison, Bernstein | Human - H3K9me3(Dot blot)
Mouse - H3K9me3 (ab8898)(Dot blot,Western blot) Mouse - H3K9me3 (ab8898)(Dot blot) |
484088 699671 943257 | GeneCard:HIST2H3C | H3K9me3 (ab8898) | |
| H3K9me3_(9754) | Rabbit polyclonal antibody was produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys9 is tri-methylated. Antibody was purified by protein A and peptide affinity chromatography. Tri-Methyl-Histone H3 (Lys9) Antibody detects endogenous levels of histone H3 only when tri-methylated on Lys9. The antibody does not cross-react with non-methylated, mono-methylated, or di-methylated Lys9. In addition, the antibody does not cross-react with non-methylated, mono-methylated, di-methylated or tri-methylated histone H3 Lys4, Lys27, Lys36 or histone H4 Lys20. Antibody Target: H3K9me3 | H3K9me3 | histone cluster 2, H3c, HIST2H3C | Cell Signaling Technology 9754 | Farnham | Human - H3K9me3 (9754)(Western blot,Peptide ELISA) | 1 | GeneCard:HIST2H3C | H3K9me3 (9754) | |
| H4K20me1 | Rabbit polyclonal. Antibody Target: H4K20me1 | H4K20me1 | Histone H4 (mono-methyl K20). Is associated with active and accessible regions. In mammals, PR-Set7 specifically catalyzes H4K20 monomethylation. NOTE CONTRAST to H3K20me3 which is associated with heterochromatin and DNA repair. | abcam ab9051 | Bernstein | Human - H4K20me1(ab9051)(Dot blot) | 104513 519198 | GeneCard:HIST2H4A | H4K20me1 (ab9051) | |
| HA-E2F1 | Mouse monoclonal antibody HA.11 clone 16B12 was raised against the twelve amino acid peptide CYPYDVPDYASL. This second-generation HA antibody is an excellent substitute for the 12CA5 monoclonal antibody. The HA.11 antibody recognizes the influenza hemagglutinin epitope (YPYDVPDYA) which has been used extensively as a general epitope tag in expression vectors. The extreme specificity of the antibody allows unambiguous identification and quantitative analysis of the tagged protein. The HA.11 antibody recognizes HA epitopes located in the middle of protein sequences as well as at the N- or C-terminus. Antibody Target: HA-E2F1 | HA-E2F1 | The HA-E2F1 protein is a derivative of E2F1, a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionary conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This version of E2F1 includes an N terminal HA tag and a modified ER ligand binding domain to allow regulated translocation to the nucleus. | Covance MMS-101P | Farnham | Human - HA-E2F1(Immunoprecipitation-Western blot,ChIP-seq) | GeneCard:E2F1 | HA-E2F1 (MMS-101P) | ||
| HCFC1_(NB100-68209) | Rabbit polyclonal antibody against residue 1700 and 1750 of human host cell factor C1 | HCFC1 | The epitope recognized by this antibody maps to a region between residue 1700 and 1750 of human host cell factor C1 (VP16-accessory protein). | Novus Biologicals NB100-68209 | Snyder | Human - HCFC1 (NB100-68209)(Immunoprecipitation,IP-MassSpec)
Mouse - HCFC1 (NB100-68209)(Immunoprecipitation,IP-MassSpec) |
A1 | GeneCard:HCFC1 | HCFC1_(NB100-68209) | |
| HDAC1_(SC-6298) | Goat polyclonal IgG affinity purified, 200 micrograms/ml, epitope mapping at the C-terminus of HDAC1 of human origin. Antibody Target: HDAC1 | HDAC1 | Histone deacetylase 1 (HDAC1) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC1 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription. Alternate names for HDAC1 include RPD3L1, HD1, GON-10, and DKFZp686H12203. | Santa Cruz Biotechnology sc-6298 | Bernstein | Human - HDAC1 (sc-6298)(Western blot,ChIP-seq) | H0509 | GeneCard:HDAC1 | HDAC1 (sc-6298) | |
| HDAC2_(A300-705A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: HDAC2 | HDAC2 | Histone deacetylase 2 (HDAC2) is a class I histone deacetylase that catalyzes the removal of the acetyl group on lysine residues of the N-terminus of the core histones H2A, H2B, H3, and H4. HDAC2 is a component of multiple deacetylating complexes such as Sin3, NuRD, and CoRest that function to repress gene transcription. Alternate names for HDAC2 include HD2, RPD3, and YAF1. | Bethyl Laboratories A300-705A | Bernstein | Human - HDAC2 (A300-705A)(Western blot,ChIP-seq) | A300-705A-1 | GeneCard:HDAC2 | HDAC2 (A300-705A) | |
| HDAC2_(SC-6296) | Goat polyclonal IgG, epitope mapping at the C-terminus of HDAC2 of human origin. Antibody Target: HDAC2 | HDAC2 | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. (provided by RefSeq) | Santa Cruz Biotechnology sc-6296 | Myers | Human - HDAC2 (sc-6296)(Immunoprecipitation-Western blot,IP-MassSpec) | G0307 | GeneCard:HDAC2 | HDAC2 (sc-6296) | |
| HDAC6_(A301-341A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: HDAC6 | HDAC6 | Histone deacetylase 6 (HDAC6) is a class II histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminus of core histones. HDAC6 has also been identified as a cytoplasmic deacetylase that acts on tubulin and HSP90 to influence cell motility. Recently HDAC6 has been found to be involved in the stress response as a component of cytoplasmic stress granules. | Bethyl Laboratories A301-341A | Bernstein | Human - HDAC6 (A301-341A)(Western blot,ChIP-String) | A301-341A-1 | GeneCard:HDAC6 | HDAC6 (A301-341A) | |
| HMGN1_(ab51212) | Rabbit polyclonal A/G affinity purified, immunogen= synthetic peptide derived from residues 50 to the C-terminus of Human HMGN1 / HMG14. Antibody Target: HMGN1 | HMGN1 | HMGN1 is one of four members of the high mobility group nucleosome binding proteins. HMGN1 is ubiquitously expressed and has been implicated in promoting transcription. | abcam ab5212 | Struhl | Human - HMGN1 (ab51212)(Western blot,Immunoprecipitation) | 128175 | GeneCard:HMGN1 | HMGN1 (ab5212) | |
| HMGN3 | Rabbit polyclonal A/G affinity purified. Raised against an amino acids 60 to 99 of human HMGN3. Vendor recommeds its use for detection of HMGN3 in human samples using immunohistochemistry. Antibody Target: HMGN3 | HMGN3 | HMGN3 is a high-mobility group protein. These proteins are small, 8 to 11 kDa, ubiquitous proteins believed to play a role in chromatin structure. HMGNs bind to nucleosomes between the histone core and DNA and reduce chromatin compaction. As a result HMGNs, HMGN3 included, are believed to increase access to DNA for DNA replication, repair and transcription. HMGN3 has specifically been implicated in the action of Thyroid horomone receptors. | Novus Biologicals NB100-61076 | Struhl | Human - HMGN3 (NB100-61076)(Western blot,Immunoprecipitation) | 1 | GeneCard:HMGN3 | HMGN3 (NB100-61076) | |
| HNF4A | Goat polyclonal IgG. Antibody Target: HNF4A | HNF4A | Epitope mapping at the C-terminus of Rab 11 of human origin | Santa Cruz Biotechnology sc-6556 | Snyder | Human - missing | GeneCard:HNF4A | HNF4A (sc-6556) | ||
| HNF4A_(SC-8987) | Rabbit polyclonal IgG, epitope corresponding to a.a. 295-465 mapping at the C-terminus of HNF4A of human origin. Antibody Target: HNF4A | HNF4A | The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes (RefSeq). | Santa Cruz Biotechnology sc-8987 | Myers | Human - HNF4A (sc-8987)(Immunoprecipitation-Western blot,IP-MassSpec) | G1309 | GeneCard:HNF4A | HNF4A (sc-8987) | |
| HNF4G_(SC-6558) | Goat polyclonal IgG, epitope mapping at the C-terminus of HNF4G of human origin. Antibody Target: HNF4G | HNF4G | Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is encoded by the HNF4G gene | Santa Cruz Biotechnology sc-6558 | Myers | Human - HNF4G (sc-6558)(Western blot,IP-MassSpec) | I299 | GeneCard:HNF4G | HNF4G (sc-6558) | |
| HSF1 | Rabbit polyclonal IgG. Antibody Target: HSF1 | HSF1 | Epitope corresponding to amino acids 219-529 of heat shock transcription factor 1 (HSF1) of human origin | Santa Cruz Biotechnology sc-9144 | Snyder | Human - HSF1(Immunoprecipitation,Motif Enrichment) | GeneCard:HSF1 | HSF1 (sc-9144) | ||
| IGF2BP1 | Rabbit polyclonal affinity purified recognizes IGF2 mRNA-binding protein 3 at the C-terminus Antibody Target: IGF2BP1 | IGF2BP1 | Insulin-like growth factor 2 mRNA binding protein 1 (Homo sapiens) | Millipore 07-104 | Tenenbaum | Human - IGF2BP1 (07-104)(Western blot,Immunoprecipitation) | NRG1665149 | GeneCard:IGF2BP1 | IGF2BP1 (07-104) | |
| IKZF1_(IkN)_(UCLA) | Rabbit polyclonal antibody raised against a recombinant protein encompassing the amino-terminus of the murine IKZF1 protein. Antibody Target: IKZF1 | IKZF1 | IKAROS family zinc finger 1 (Ikaros or IKZF1) is a C2H2 zinc finger transcription factor that is associated with various chromatin-modifying complexes and is suggested to play a role in the development of lymphocytes, B- and T-cells. | Dr. Stephen Smale at UCLA IKZF1_(IkN) | Farnham | Human - IKZF1 (IkN) (UCLA)(Western blot,ChIP-seq) | GeneCard:IKZF1 | IKZF1 (IKZF1 (IkN)) | ||
| IRF1 | Rabbit polyclonal. IRF-1 (C-20) is an affinity purified antibody raised against a peptide mapping at the C-terminus of IRF-1 of human origin. Antibody Target: IRF1 | IRF1 | Interferon regulatory factor 1 is a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription and also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. IRF1 has been shown to play roles in regulating apoptosis and tumor suppression. | Santa Cruz Biotechnology sc-497 | Farnham | Human - missing | GeneCard:IRF1 | IRF1 (sc-497) | ||
| IRF3 | Rabbit polyclonal. Epitope corresponding to amino acids 1-425 of IRF-3 of human origin. Antibody Target: IRF3 | IRF3 | Mediates interferon-stimulated response element (ISRE) promoter activation. DsRNA leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. | Santa Cruz Biotechnology sc-9082 | Snyder | Human - IRF3(Immunoblot) | GeneCard:IRF3 | IRF3 (sc-9082) | ||
| IRF4_(SC-6059) | Goat polyclonal IgG, epitope mapping at the C-terminus of IRF-4 of mouse origin. Antibody Target: IRF4 | IRF4 | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family. It functions as a lymphocyte specific transcription factor and negatively regulates TLR signaling by selectively competing with IRF5. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma (RefSeq). | Santa Cruz Biotechnology sc-6059 | Myers | Human - IRF4 (sc-6059)(Immunoprecipitation-Western blot,IP-MassSpec) | IO1O6 | GeneCard:IRF4 | IRF4 (sc-6059) | |
| IRF9_(SC-496) | Rabbit polyclonal, epitope mapping at the C-terminus of IRF9 of human origin. Antibody Target: IRF9 | IRF9 | Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state (provided by RefSeq) | Santa Cruz Biotechnology sc-496 | Myers | Human - IRF9 (sc-496)(Western blot,IP-MassSpec) | A1111 K1302 | GeneCard:IRF9 | IRF9 (sc-496) | |
| c-Jun | Rabbit polyclonal to amino acids 1-79 mapping at the N-terminus of c-Jun p39 of human origin. Antibody Target: JUN | JUN | Heterodimer of Fos and Jun constitute transcription factor AP1. Proto-oncogene c-Jun is a leucine-zipper. | Santa Cruz Biotechnology sc-1694 | Snyder | Human - c-Jun(Immunoprecipitation,Motif Enrichment)
Mouse - c-Jun(Immunoprecipitation,ChIP-seq) |
C2206 | GeneCard:JUN | c-Jun (sc-1694) | |
| JunD | Rabbit polyclonal IgG. Antibody Target: JUND | JUND | The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. (provided by RefSeq) | Santa Cruz Biotechnology sc-74 | Myers, Snyder | Human - JunD(sc-74)(Western blot,IP-MassSpec)
Mouse - missing |
GeneCard:JUND | JUND (sc-74) | ||
| KAP1 | Rabbit polyclonal. Immunogen was a synthetic peptide, which represented a portion of human tripartite motif-containing 28 (KAP1) encoded within exon 1. Antibody Target: TRIM28 | KAP1 | KRAB Associated Protein 1, helps regulate transcriptional repression. | abcam ab10483 | Farnham | Human - KAP1(Western blot,Immunoprecipitation-Western blot) | 193224 | GeneCard:TRIM28 | KAP1 (ab10483) | |
| GCN5 | Rabbit polyclonal anti-GCN5 antibody (2676), Immunogen: synthetic peptide coupled to Ovalbumin (sequence-MAEPSQAPTPAPAAQPRPLC). Antibody Target: KAT2A | KAT2A | KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. Acetylation of histones gives a specific tag for epigenetic transcription activation. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the SAGA and ATAC complexes, complexes with histone acetyltransferase activities on histones H3 and H4 | Dr. Lazlo Tora at Institut de Gènètique et de Biologie Molèculaire et Cellulaire GCN5 (2676) | Struhl | Human - missing | GeneCard:KAT2A | GCN5 | ||
| PCAF | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Taget: KAT2B | KAT2B | PCAF (P300/CBP-associated factor) is a histone acetyltransferase (HAT) identified as a factor that associates with P300/CBP, a transcriptional coactivator of nuclear hormone receptors and other transcription factors. | Bethyl Laboratories A301-666A | Bernstein | Human - PCAF (A301-666A)(ChIP-seq,Western blot) | A301-666A-1 | GeneCard:KAT2B | PCAF/KAT2B (A301-666A) | |
| LSD1 | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Target: KDM1A | KDM1A | BHC110/LSD1 is a histone demethylase and a component of several histone deacetylase complexes. BHC110/LSD1 is able to specifically catalyze the demethylation of Lys4 of histone H3. As part of histone deacetylase complexes BHC110/LSD1 functions as a corepressor of transcription. | Bethyl Laboratories A300-215A | Bernstein | Human - LSD1 (A300-215A)(ChIP-seq,Western blot) | A300-215A-1 | GeneCard:KDM1A | LSD1/KDM1A (A300-215A) | |
| JMJD2A_(A300-861A-1) | Rabbit polyclonal antigen affinity purified, unconjugated, liquid. Antibody Target: KDM4A | KDM4A | JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. | Bethyl Laboratories A300-861A | Bernstein | Human - JMJD2A (A300-861A)(ChIP-seq,Western blot) | A300-861A-1 | GeneCard:KDM4A | JMJD2A (A300-861A) | |
| JARID1A_(ab26049) | Rabbit polyclonal to KDM5A / Jarid1A / RBBP2. Antibody Target: KDM5A | KDM5A | Histone demethylase that specifically demethylates | abcam ab26049 | Bernstein | Human - JARID1A (ab26049)(Western blot,ChIP-seq) | 910477 | GeneCard:KDM5A | JARID1A (ab26049) | |
| PLU1 | Rabbit polyclonal Antigen Anti-PLU-1 Affinity Purified, Unconjugated, Liquid. Antibody Target: KDM5B | KDM5B | JARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer. Alternative names for JARID1B include retinoblastoma-binding protein 2 homolog 1, RBP2-H1, cancer/testis antigen 31, CT31, PLU-1, PUT1, and KDM5B. | Dr. Yang Shi at Harvard PLU-1 | Bernstein | Human - PLU1(Western blot,ChIP-seq) | GeneCard:KDM5B | PLU-1 | ||
| LEF1_(SC-8592) | Goat polyclonal IgG, epitope mapping near the C-terminus of LEF1 of human origin. Antibody Target: LEF1 | LEF1 | This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The proteins encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity (RefSeq). | Santa Cruz Biotechnology sc-8592 | Myers | Human - LEF1 (sc-8592)(Immunoprecipitation-Western blot,IP-MassSpec) | C2409 | GeneCard:LEF1 | LEF1 (sc-8592) | |
| MafF_(M8194) | Rabbit polyclonal. Raised against synthetic peptide corresponding to amino acids 147-163 of human MAFF. The immunizing peptide does not cross-react with other members of the family. Antibody Target: MAFF | MAFF | The protein encoded by this gene is a (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. Can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. May also be involved in the cellular stress response. | Sigma-Aldrich M8194 | Snyder | Human - missing | GeneCard:MAFF | MAFF (M8194) | ||
| MafK_(ab50322) | Rabbit polyclonal. Raised against synthetic peptide: TTNPKPNKALKVKKEA conjugated to KLH by a C-terminal Cysteine residue linker, corresponding to amino acids 2-17 of Human MAFK. Antibody Target: MAFK | MAFK | NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP)proteins. Since they lack a putative transactivation domain, small Mafs behave as transcriptional repressors when they dimerize among themselves. They serve as transcriptional activators by dimerizing with other (usually larger) bZip proteins and recruiting them to specific DNA-binding sites. | abcam ab50322 | Snyder | Human - MAFK (ab50322)(Immunoprecipitation,ChIP-seq)
Mouse - MAFK (ab50322)(Immunoprecipitation,ChIP-seq) |
904274 | GeneCard:MAFK | MAFK (ab50322) | |
| MafK_(SC-477) | Rabbit polyclonal raised against epitope mapping at the C-terminus of NF-E2 p18 of mouse origin; recommended for detection of NF-E2 p18 (MafK) of mouse, rat and human origin. Antibody Target: MAFK | MAFK | NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP)proteins. Since they lack a putative transactivation domain, small Mafs behave as transcriptional repressors when they dimerize among themselves. They serve as transcriptional activators by dimerizing with other (usually larger) bZip proteins and recruiting them to specific DNA-binding sites. | Santa Cruz Biotechnology sc-477 | Snyder | Human - MafK(sc-477)(Immunoprecipitation,ChIP-seq) | K1709 | GeneCard:MAFK | MAFK (sc-477) | |
| Max | Rabbit polyclonal IgG affinty purified, epitope mapping at the C-terminus of Max of human origin. Antibody Target: MAX | MAX | The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown (RefSeq). | Santa Cruz Biotechnology sc-197 | Myers, Snyder | Human - MAX(sc-197)(Immunoprecipitation,Motif Enrichment)
Mouse - MAX(sc-197)(Immunoprecipitation,Motif Enrichment) |
J0809 | GeneCard:MAX | MAX (sc-197) | |
| MAZ_(ab85725) | Rabbit polyclonal affinity purified, immunogen is synthetic peptide, corresponding to a region within amino acids 427-477 of Human MAZ, GenBank BAA33064.1. Antibody Target: MAZ | MAZ | May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. | abcam ab85725 | Snyder | Human - MAZ(ab85725)(Immunoprecipitation,IP-MassSpec)
Mouse - MAZ(ab85725)(Immunoprecipitation,IP-MassSpec) |
GR41711-2 | GeneCard:MAZ | MAZ (ab85725) | |
| MBD4_(SC-271530) | Mouse monoclonal IgG, specific for an epitope mapping between a.a. 515-555 within an internal region of MBD4 of mouse origin. Antibody Target: MBD4 | MBD4 | MBD4 may function to mediate the biological consequences of the methylation signal. In addition, MBD4 has protein sequence similarity to bacterial DNA repair enzymes and thus may have some function in DNA repair. Further, MBD4 gene mutations are detected in tumors with primary microsatellite-instability (MSI), a form of genomic instability associated with defective DNA mismatch repair, and MBD4 gene meets 4 of 5 criteria of a bona fide MIS target gene. (provided by RefSeq) | Santa Cruz Biotechnology sc-271530 | Myers | Human - MBD4 (sc-271530)(Western blot,IP-MassSpec) | A1111 H1210 | GeneCard:MBD4 | MBD4 (sc-271530) | |
| Med1_(sc-8998) | Rabbit polyclonal A/G affinity purified, epitope corresponding to amino acids 502-756 of TRAP220 of mouse origin. Antibody Target: MED1 | MED1 | MED1 is a core subunit of the large coactivator known as mediator. Mediator is believed to promote transcription by bridging transcription factors and the RNA polymerase II holoenzyme. | Santa Cruz Biotechnology sc-8998 | Struhl | Human - Med1 (sc-8998)(Western blot,Immunoprecipitation) | GeneCard:MED1 | MED1 (sc-8998) | ||
| Med26_(sc-48776) | Rabbit polyclonal A/G affinity purified, epitope corresponding to amino acids 373-600 mapping at the C-terminus of CRSP70 of human origin. Antibody Target: MED26 | MED26 | MED26 is a subunit of the large coactivator known as mediator. MED26 is subunit found to be mutually exclusive from the CDK8 module of mediator. MED26 has been associated with activating effects on transcription in context specific manner. Mediator is believed to promote transcription by bridging transcription factors and the RNA polymerase II holoenzyme. | Santa Cruz Biotechnology sc-48776 | Struhl | Human - Med26 (sc-48776)(Western blot,Immunoprecipitation) | GeneCard:MED26 | MED26 (sc-48776) | ||
| MEF2A | Rabbit polyclonal IgG, epitope mapping at the C-terminus of MEF-2 of human origin. Antibody Target: MEF2A | MEF2A | The protein encoded by this gene is a DNA-binding transcription factor that activates many muscme-specific, growth factor-induced, and stress-induced genes. | Santa Cruz Biotechnology sc-313 | Myers | Human - MEF2A(Immunoblot) | GeneCard:MEF2A | MEF2A (sc-313) | ||
| MEF2C_(SC-13268) | Goat polyclonal IgG, epitope mapping near the C-terminus of MEF2C of human origin. Antibody Target: MEF2C | MEF2C | This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. (provided by RefSeq) | Santa Cruz Biotechnology sc-13268 | Myers | Human - MEF2C (sc-13268)(Western blot,Motif Enrichment) | K2009 | GeneCard:MEF2C | MEF2C (sc-13268) | |
| MTA3_(SC-81325) | Mouse monoclonal IgG, raised against a recombinant protein corresponding to a region near the N-terminus of MTA3 of human origin. Antibody Target: MTA3 | MTA3 | Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. | Santa Cruz Biotechnology sc-81325 | Myers | Human - MTA3 (sc-81325)(Western blot,IP-MassSpec) | F1110 | GeneCard:MTA3 | MTA3 (sc-81325) | |
| Mxi1_(AF4185) | Goat polyclonal IgG affinity purified, raised against E. coli-derived rhMxi1. Antibody Target: MXI1 | MXI1 | Transcriptional repressor. Binds with MAX to form recognize the core sequence 5'-CAC[GA]TG-3', antagonizes MYC transcriptional activity by competing for MAX | R&D Systems AF4185 | Snyder | Human - MXI1(Immunoprecipitation,IP-MassSpec)
Mouse - MXI1(Immunoprecipitation,IP-MassSpec) |
ZIJ0107031 | GeneCard:MXI1 | MXI1 (AF4185) | |
| c-Myb_(SC-7874) | Rabbit polyclonal IgG, Epitope corresponding to amino acids 500-640 mapping at the C-terminus of c-Myb of human origin. Antibody Target: MYB | MYB | Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. | Santa Cruz Biotechnology sc-7874 | Snyder | Mouse - missing | GeneCard:MYB | c-Myb (sc-7874) | ||
| MYBL2_(SC-81192) | Mouse monoclonal IgG, raised against a recombinant protein corresponding to an internal region of B-Myb of human origin. Antibody Target: MYBL2 | MYBL2 | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined. (provided by RefSeq) | Santa Cruz Biotechnology sc-81192 | Myers | Human - MYBL2 (sc-81192)(Western blot,IP-MassSpec) | B1611 | GeneCard:MYBL2 | MYBL2 (sc-81192) | |
| c-Myc | Rabbit polyclonal affinity purified to amino acids 1-262 of c-Myc human origin. Antibody Target: MYC | MYC | transcription factor; c-Myc-encoded proteins function in cell proliferation,differentiation and neoplastic disease | Santa Cruz Biotechnology sc-764 | Crawford, Snyder | Human - c-Myc (sc-764)(Western blot)
Mouse - c-Myc (sc-764)(Immunoprecipitation,ChIP-seq) |
H0107 | GeneCard:MYC | c-Myc (sc-764) | |
| MyoD_(sc-32758) | Mouse monoclonal antibody raised against recombinant MYOD of mouse origin with an epitope mapping to amino acids 180-189. Antibody Target: MYOD1 | MYOD1 | This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. (provided by RefSeq) | Santa Cruz Biotechnology sc-32758 | Wold | Mouse - missing | GeneCard:MYOD1 | MYOD (sc-32758) | ||
| Myogenin_(sc-12732) | Mouse monoclonal antibody; epitope mapping within amino acids 138-158 of myogenin of rat origin. Antibody Target: MYOG | MYOG | Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. (provided by RefSeq) | Santa Cruz Biotechnology sc-12732 | Wold | Mouse - missing | GeneCard:MYOG | Myogenin (sc-12732) | ||
| NANOG_(SC-33759) | Rabbit polyclonal IgG, epitope corresponding to amino acids 151-305 mapping at the C-terminus of Nanog of human origin. Antibody Target: NANOG | NANOG | Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity) (provided by RefSeq). | Santa Cruz Biotechnology sc-33759 | Myers | Human - NANOG (sc-33759)(Western blot,IP-MassSpec) | C0909 | GeneCard:NANOG | NANOG (sc-33759) | |
| NCoR | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid Antibody Target: NCOR1 | NCOR1 | The nuclear receptor corepressor protein (NCoR) mediates gene repression by interacting with nuclear receptors. NCoR mediates repression by associating with SIN3A/B and the histone deacetylases, HDAC1 and HDAC2, and promoting the formation of repressive chromatin structures. | Bethyl Laboratories A301-145A | Bernstein | Human - NCOR (A301-145A)(ChIP-seq,Western blot) | A301-145A-1 | GeneCard:NCOR1 | NCoR (A301-145A) | |
| NFATC1_(SC-17834) | Mouse monoclonal IgG, raised against amino acids 1-110 of NFATc1 of human origin. Antibody Target: NFATC1 | NFATC1 | The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. (provided by RefSeq) | Santa Cruz Biotechnology sc-17834 | Myers | Human - NFATC1 (sc-17834)(Western blot,IP-MassSpec) | G2007 | GeneCard:NFATC1 | NFATC1 (sc-17834) | |
| NF-E2 | Rabbit polyclonal, epitope mapping at the C-terminus of NFE2 of mouse origin and recommended for detection of protein of rat, mouse and human origin. Antibody Target: NFE2 | NFE2 | Nuclear factor, erythroid-derived 2 | Santa Cruz Biotechnology sc-291 | Snyder | Human - missing | D1703 | GeneCard:NFE2 | NF-E2 (sc-291) | |
| NF-E2_(SC-22827) | Rabbit polyclonal, epitope: 1-230 mapping at the N-terminus of NFE2 of human origin. Antibody Target: NFE2 | NFE2 | Transcription factor NFE2 45 kDa subunit is a component of the NFE2 complex and essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2)recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NFE2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. NFE2 has been shown to interact with CREB binding protein. | Santa Cruz Biotechnology sc-22827 | Snyder | Human - missing | GeneCard:NFE2 | NF-E2 (sc-22827) | ||
| NFIC_(SC-81335) | Mouse monoclonal IgG, raised against a recombinant protein corresponding to an internal region of NF-1 of human origin. Antibody Target: NFIC | NFIC | Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | Santa Cruz Biotechnology sc-81335 | Myers | Human - NFIC (sc-81335)(Western blot,IP-MassSpec) | L0808 | GeneCard:NFIC | NFIC (sc-81335) | |
| NF-YA | Rabbit polyclonal affinity purified raised against amino acids 139-347 of recombinant human NFYA. Antibody Target: NFYA | NFYA | NFYA is the alpha subunit of the trimeric NFY transcription factor complex that binds to the ubiquitous CCAAT motif | Dr. R. Mantovani at Universita degli Studi di Milano NF-YA | Struhl | Human - NF-YA(Western blot,Immunoprecipitation) | GeneCard:NFYA | NF-YA | ||
| NF-YB | Rabbit polyclonal affinity purified raised against recombinant full length human NFYB. Antibody Target: NFYB | NFYB | NFYB is the beta subunit of the trimeric NFY transcription factor complex that binds to the ubiquitous CCAAT motif | Dr. R. Mantovani at Universita degli Studi di Milano NF-YB | Struhl | Human - NF-YB(Western blot,Immunoprecipitation) | GeneCard:NFYB | NF-YB | ||
| TR4 | Rabbit polyclonal affinity purified Anti-TR4. Antibody Target: NR2C2 | NR2C2 | (Also: NR2C2) Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. | Dr. J.D. Engel at University of Michigan TR4 | Farnham | Human - TR4 (Western blot,ChIP-seq) | GeneCard:NR2C2 | TR4 | ||
| NR2F2_(SC-271940) | Mouse monoclonal IgG affinity purified, specific for an epitope mapping between amino acids 13-44 at the N-terminus of NR2F2 of human origin. Antibody Target: NR2F2 | NR2F2 | This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. (provided by RefSeq) | Santa Cruz Biotechnology sc-271940 | Myers | Human - NR2F2 (sc-271940)(Western blot,IP-MassSpec) | I1410 | GeneCard:NR2F2 | NR2F2 (sc-271940) | |
| GR | Rabbit polyclonal. Anti-GR. Antibody Target: NR3C1 | NR3C1 | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | Santa Cruz Biotechnology sc-1003 | Myers | Human - GR(Immunoblot) | A2508 E1908 | GeneCard:NR3C1 | GR (sc-1003) | |
| Nrf1 | Mouse monoclonal A/G affinity purified, Immunogen corresponding to amino acids 201-286 of Human NRF1. Antibody Target: NRF1 | NRF1 | NRF1 is the mammalian homolog to the erect wing (ewg) Drosophila protein that is required for proper development of the central nervous system and indirect flight muscles. In mammals NRF1 functions as a transcription factor that activates the expression of the EIF2S1 (EIF-alpha) gene. This protein links the transcriptional modulation of key metabolic genes to cellular growth and development, and has been implicated in the control of nuclear genes required for respiration, heme biosynthesis and mitochondrialDNA transcription and replication. NRF1 forms a homodimer and binds DNA as a dimer. NRF1 shows a nuclear localization and is expressed widely in embryonic, fetal and adult tissues. Phosphorylation of NRF1 enhances DNA binding. | abcam ab55744 | Snyder | Human - NRF1(Immunoblot,Motif Enrichment) | GR27905 | GeneCard:NRF1 | NRF1 (ab55744) | |
| PABPC1 | Mouse monoclonal. Raised against fusion protein corresponding to full-length human poly (A)-binding protein PABP. Antibody Target: PABPC1 | PABPC1 | Poly(A) binding protein, cytoplasmic 1 (Homo sapiens). | Millipore 04-1467 | Tenenbaum | Human - PABPC1 (04-1467)(Western blot,Immunoprecipitation) | JBC1363217 | GeneCard:PABPC1 | PABPC1 (04-1467) | |
| PAX5-C20 | Goat polyclonal IgG, 200 micrograms/ml. Epitope mapping at the C-terminus of Pax-5 of human origin. Antibody Target: PAX5 | PAX5 | This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. | Santa Cruz Biotechnology sc-1974 | Myers | Human - PAX5-C20(Immunoprecipitation-Western blot,IP-MassSpec) | E1409 | GeneCard:PAX5 | PAX5 (sc-1974) | |
| PAX5-N19 | Goat polyclonal IgG epitope mapping at the N-terminus of Pax-5 of human origin. Antibody Target: PAX5 | PAX5 | This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. | Santa Cruz Biotechnology sc-1975 | Myers | Human - PAX5-N19(Immunoprecipitation-Western blot,IP-MassSpec) | I070 | GeneCard:PAX5 | PAX5 (sc-1975) | |
| PAX5_(N-15) | Rabbit polyclonal antibody; epitope is a synthetic peptide: MDLEKNYPTPRTSRT, corresponding to amino acids 1-15 of Human PAX5, cross-reacts with human and mouse PAX5. Antibody Target: PAX5 | PAX5 | The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B cell differentiation. | abcam ab12000 | Hardison | Mouse - PAX N-15(Western blot) | 853694 | GeneCard:PAX5 | PAX5 (ab12000) | |
| Pbx3 | Rabbit polyclonal IgG. Antibody Target: PBX3 | PBX3 | Pbx 3 (D-17) | Santa Cruz Biotechnology sc-891 | Myers | Human - PBX3(sc-891)(Western blot) | H0307 | GeneCard:PBX3 | PBX3 (sc-891) | |
| PHF8_(A301-772A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: PHF8 | PHF8 | PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate. PHF8 is also known as ZNF422 and KIAA1111. | Bethyl Laboratories A301-772A | Bernstein | Human - PHF8 (A301-772A)(Western blot,ChIP-seq) | A301-772A-1 | GeneCard:PHF8 | PHF8 (A301-772A) | |
| PITX1_(SC-81979) | Mouse monoclonal IgG, raised against recombinant Pitx1 of human origin. Antibody Target: PITX1 | PITX1 | This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. (provided by RefSeq) | Santa Cruz Biotechnology sc-81979 | Myers | Human - PITX1 (sc-81979)(Immunoprecipitation-Western blot,IP-MassSpec) | J0109 | GeneCard:PITX1 | PITX1 (sc-81979) | |
| PML_(SC-71910) | Mouse monoclonal IgG, N-terminal epitope corresponding to residues 37-51 of PML of human origin. Antibody Target: PML | PML | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq) | Santa Cruz Biotechnology sc-71910 | Myers | Human - PML (sc-71910)(Western blot,IP-MassSpec) | H1908 | GeneCard:PML | PML (sc-71910) | |
| Pol2 | Mouse monoclonal, clone 8WG16. Antibody Target: POLR2A | POLR2A | RNA Polymerase II | Covance MMS-126R | Farnham, Iyer, Snyder | Human - Pol2(Immunoprecipitation,IP-MassSpec)
Mouse - Pol2(Immunoprecipitation,IP-MassSpec) |
14861301 14922701 E11BF0034 | GeneCard:POLR2A | POL2 (MMS-126R) | |
| Pol2(phosphoS2) | Rabbit polyclonal affinity purified against peptide conjugated to KLH derived from within residues 1600 - 1700 of S. cerevisiae RNA polymerase II CTD repeat YSPTSPS, phosphorylated at S2. Antibody Target: POLR2A | POLR2A | RNA polymerase II, large subunit- specific for phosphorylated C-terminal domain. | abcam ab5095 | Snyder | Human - POL2S2 (ab5095)(Immunoprecipitation,IP-MassSpec)
Mouse - PolIIS2 (ab5095)(Immunoprecipitation,IP-MassSpec) |
GR32890-1 | GeneCard:POLR2A | POL2 (phospho S2) (ab5095) | |
| Pol2-4H8 | Mouse monoclonal to RNA polymerase II CTD repeat YSPTSPS antibody (4H8) - ChIP Grade. Antibody Target: POLR2A | POLR2A | This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. | abcam ab5408 | Myers,Hardison | Human - Pol2-4H8(Western blot,IP-MassSpec)
Mouse - Pol2-4H8(ab5408)(Western blot) |
648628 647708 722997 962594 | GeneCard:POLR2A | Pol2-4H8 (ab5408) | |
| Pol3 | Mouse monoclonal IgG1. Antibody Target: POLR3G | POLR3G | RNA Polymerase III | Santa Cruz Biotechnology sc-21754 | Snyder | Human - Pol3(Immunoprecipitation,IP-MassSpec) | D4104 | GeneCard:POLR3G | POL III(sc-21754) | |
| POU2F2 | Rabbit polyclonal. Oct-2(C-20) is an affinity purified antibody raised against a peptide mapping at the C-terminus of Oct-2 of human origin. Antibody Target: POU2F2 | POU2F2 | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. | Santa Cruz Biotechnology sc-233 | Myers | Human - POU2F2(Immunoprecipitation-Western blot,IP-MassSpec) | C2609 | GeneCard:POU2F2 | POU2F2 (sc-233) | |
| POU5F1_(SC-9081) | Rabbit polyclonal IgG, epitope corresponding to amino acids 1-134 of Oct3/4 of human origin. Antibody Target: POU5F1 | POU5F1 | This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12 (provided by RefSeq). | Santa Cruz Biotechnology sc-9081 | Myers | Human - POU5F1 (sc-9081)(Western blot,IP-MassSpec) | F2609 | GeneCard:POU5F1 | POU5F1 (sc-9081) | |
| PGC1A | Rabbit polyclonal IgG. PGC-1 Antibody (H-300) Epitope corresponding to amino acids 1-300 mapping at the N-terminus of PPARPγ coactivator-1 (PGC-1) of human origin. Antibody Target: PPARGC1A | PPARGC1A | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). | Santa Cruz Biotechnology sc-13067 | Snyder | Human - missing | GeneCard:PPARGC1A | PGC1A (sc-13067) | ||
| PRDM1_(9115) | Rabbit monoclonal antibody against a synthetic peptide corresponding to residues surrounding Val90 of human PRDI-BF1. Antibody Target: PRDM1 | PRDM1 | Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. | Cell Signaling Technology 9115 | Snyder | Human - missing | GeneCard:PRDM1 | PRDM1 (9115) | ||
| Rad21 | Rabbit polyclonal affinity purified. Antibody Target: RAD21 | RAD21 | Synthetic peptide (Human) conjugated to KLH - which represents a portion of human Rad21 encoded within exon 14 | abcam ab992 | Snyder | Human - RAD21(Western blot,siRNA)
Mouse - Rad21 (ab992)(Immunoprecipitation,siRNA) |
940739 891751 734371 | GeneCard:RAD21 | RAD21 (ab992) | |
| RBBP5_(A300-109A) | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: RBBP5 | RBBP5 | Retinoblastoma binding protein 5 (RbBP5) is a subunit of a human Set1-like histone methyltransferase (HMT) complex. The Set-1 like complexes are responsible for mono-, di-, and tri-methylation of histone H3 K4. RbBP5 associates with a multitude of proteins in a number of Set1-like complexes which include various combinations of MLL, MLL2, MLL3, MLL4, ASH2L,WDR5, hDPY-30, hSwd2, CXXC1, HCF1, Menin, PTIP, PA1, NCOA6, and UTX. RbBP5 is also one of many proteins that bind the Retinoblastoma tumor suppressor protein, pRb. Alternate names for RbBP5 are RBQ3 and SWD1. | Bethyl Laboratories A300-109A | Bernstein | Human - RBBP5 (A300-109A)(Western blot,ChIP-seq) | A300-109A-2 | GeneCard:RBBP5 | RBBP5 (A300-109A) | |
| COREST_(ab24166) | Rabbit polyclonal affinity purified, synthetic peptide conjugated to KLH derived from within residues 400 to the C-terminus of Human CoREST. Note: This antibody has since been discontinued. Full product information is attached as part of validation document. Antibody Target: RCOR1 | RCOR1 | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. | abcam ab24166 | Snyder | Human - COREST (ab24166)(Western blot,ChIP-seq) | 834865 | GeneCard:RCOR1 | RCOR1/COREST (ab24166) | |
| COREST_(sc-30189) | Rabbit polyclonal, epitope corresponding to amino acids 246-310 mapping within an internal region of CoREST of human origin Antibody Target: RCOR1 | RCOR1 | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. | Santa Cruz Biotechnology sc-30189 | Snyder | Human - COREST (sc-30189)(Immunoprecipitation,ChIP-seq)
Mouse - COREST (sc-30189)(Immunoprecipitation,ChIP-seq) |
C0806 | GeneCard:RCOR1 | RCOR1/COREST (sc30189) | |
| NELFe | Rabbit polyclonal A/G affinity purified NELF-E (RDBP). Antibody Target: RDBP | RDBP | NELF-E (RDBP) is a part of the negative elongation factor complex which binds to RNAPII to suppress elongation. | Santa Cruz Biotechnology sc-32912 | Struhl | Human - NELFe (sc-32912)(Western blot,ChIP-seq)
Mouse - missing |
GeneCard:RDBP | NELF-E (sc-32912) | ||
| NFKB | Rabbit polyclonal IgG affinity purified. Epitope mapping at the C-terminus of NFKB p65 of human origin. Antibody Target: RELA | RELA | Epitope mapping at the C-terminus of NF-kappa-B p65 of human origin, recommended for detection of NFKB p65 | Santa Cruz Biotechnology sc-372 | Snyder | Human - NFKB(Immunoprecipitation,Motif Enrichment) | A2298 | GeneCard:RELA | NFKB (sc-372) | |
| NRSF | Mouse monoclonal. Antibody Target: REST | REST | Neuron-restrictive silencer transcription factor | Dr. David Anderson at Protein Expression Center (pec@caltech.edu) NRSF | Myers, Wold | Human - NRSF (Western blot,Motif Enrichment)
Mouse - missing |
20070905JV | GeneCard:REST | NRSF | |
| REST | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid | REST | A transcriptional repressor which represses neuronal genes in non-neuronal tissues. A member of the Kruppel-type zinc finger transcription factor family. Represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element (NRSE) by associating with two corepressors, mSin3 and CoREST, which recruit HDACs to the promoters of REST-regulated genes. Target is GST fusion amino acids 801-1097 of human REST. | Millipore 17-641 | Bernstein | Human - REST (17-641)(ChIP-seq,Western blot) | JH1786670 | GeneCard:REST | REST (17-641) | |
| RFX5_(200-401-194) | Rabbit polyclonal against RFX5 peptide corresponding to a region at amino acids 320 to 494 of the human protein conjugated to Keyhole Limpet Hemocyanin. Antibody Target: RFX5 | RFX5 | Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding betweenRFX and NF-Y. RFX binds the X1 box of MHC-II promoters | Rockland Immunochemicals 200-401-194 | Snyder | Human - RFX5 (200-401-194)(Western blot,Motif Enrichment) | 14562 | GeneCard:RFX5 | RFX5 (200-401-194) | |
| RNF2 | Rabbit polyclonal Antigen Affinity Purified, Unconjugated, Liquid | RNF2 | Ring finger protein 2 (RNF2) is a polycomb group (PcG) protein. RNF2 has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). | Bethyl Laboratories A302-869A | Bernstein | Human - RNF2 (A302-869A)(ChIP-seq,Western blot) | A302-869A-1 | GeneCard:RNF2 | RNF2 (A302-869A) | |
| RPC155 | Rabbit polyclonal - Antiserum 1900 was raised by immunizing rabbits with synthetic peptide PKRPLTFDTNEFHIPLVT (residues 1374?1391 of the RPC155 subunit of human pol III) coupled to KLH. Antibody Target: RPC155 | RPC155 | polymerase (RNA) III (DNA directed) polypeptide A, 155kDa | Dr. Robert J. White at Beatson Institute for Cancer Research 1900 | Struhl | Human - RPC155(1900)(Western blot,Correlation) | GeneCard:POLR3A | RPC155 (1900) | ||
| RUNX3_(SC-101553) | Mouse monoclonal IgG, raised against amino acids 191-300 of recombinant RUNX3 of human origin. Antibody Target: RUNX3 | RUNX3 | This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) | Santa Cruz Biotechnology sc-101553 | Myers | Human - RUNX3 (sc-101553)(Western blot,IP-MassSpec) | B0909 | GeneCard:RUNX3 | RUNX3 (sc-101553) | |
| RXRA | Rabbit polyclonal. RXRa(D-20) is an affinity purified antibody raised against a peptide mapping at the N-terminus of RXRalpha of human origin. Antibody Target: RXRA | RXRA | Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. | Santa Cruz Biotechnology sc-553 | Myers | Human - RXRA(Immunoprecipitation-Western blot,IP-MassSpec) | C1811 | GeneCard:RXRA | RXRA (sc-553) | |
| SAP30_(39731) | Rabbit polyclonal SAP30 antibody (pAb) raised against recombinant full length human SAP30 protein. Antibody Target: SAP30 | SAP30 | SAP30, also known asSin3A-associated protein, 30kDa, is part of the SIN3 corepressor complex, that also includes SIN3, SAP18,HDAC1,HDAC2,RbAp46andRbAp48. SAP30 is involved in the functional recruitment of the Sin3-histone deacetylase complex to a specific subset of N-CoR corepressor complexes. | Active Motif 39731 | Bernstein | Human - SAP30 (39731)(Western blot,ChIP-seq) | 4710001 | GeneCard:SAP30 | SAP30 (39731) | |
| ESET_(166621) | Mouse monoclonal IgG2b affinity purified, specific for an epitope mapping between amino acids 1195-1228 near the C-terminus of human ESET. Antibody Target: SETDB1 | SETDB1 | ERG-associated protein with SET domain (ESET), also designated Histone H3-K9 methyltransferase 4 or SET domain bifurcated 1, is a nuclear protein belonging to the histone-lysine methyltransferase family. ESET is a histone methyltransferase, methylating Lys-9 of histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. | Santa Cruz Biotechnology sc-166621 | Bernstein | Human - ESET (166621)(ChIP-seq,Western blot) | H2009 | GeneCard:SETDB1 | ESET/SETDB1 (sc-166621) | |
| SETDB1 | Rabbit polyclonal affinity purified. Antibody Target: SETDB1 | SETDB1 | SET domain, bifurcated 1, the SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure | Proteintech 11231-1-AP | Farnham | Human - SETDB1(Western blot,ChIP-seq) | 2 | GeneCard:SETDB1 | SETDB1 (11231-1-AP) | |
| SETDB1_(SC-66884) | Rabbit polyclonal. SETDB1 (H-300) is an affinity purified antibody raised against an epitope corresponding to amino acids 1-300 mapping at the N-terminus of the human SETDB1 protein. Antibody Target: SETDB1 | SETDB1 | SETDB1 is a H3K9-selective histone methyltransferase, methylating Lys-9 of Histone H3 and mutations within the SETDB1 gene abolishes its methyltransferase activity. This methylation acts is thought to play a role in transcriptional repression through HP1 protein recruitment to methylated histones. | Santa Cruz Biotechnology sc-66884 | Farnham | Human - SETDB1 (sc-66884)(Immunoprecipitation,Western blot,ChIP-seq) | GeneCard:SETDB1 | SETDB1 (sc-66884) | ||
| SIN3A_(NB600-1263) | Rabbit polyclonal, Immunogen: Synthetic peptide: MKRRLDDQESDVYAAQQRR, corresponding to amino acids 1-19 of Mouse mSin3A. Antibody Target: SIN3A (NB600-1263) | SIN3A | Mammalian Sin 3 (mSin 3) is closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. Containing 4 paired amphipathic helix domains (PAH domains), mSin 3A and mSin 3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC 1, HDAC 2, RbAp 46, the methyl CpG binding protein MeCP 2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR). | Novus Biologicals NB600-1263 | Snyder | Human - SIN3A (NB600-1263)(Immunoprecipitation,ChIP-seq)
Mouse - SIN3A (NB600-1263)(Immunoprecipitation) |
LB140235 | GeneCard:SIN3A | SIN3A (NB600-1263) | |
| Sin3Ak-20 | Rabbit polyclonal, Sin3A (k-20). Antibody Target: SIN3AK20 | SIN3AK20 | Co-repressor interacting with HDAC1, N-coR, SMRT, and MeCP2 | Santa Cruz Biotechnology sc-994 | Myers | Human - Sin3Ak-20(Immunoprecipitation-Western blot,IP-MassSpec) | F1005 | GeneCard:SIN3A | SIN3AK20 (sc-994) | |
| SIRT6 | Rabbit polyclonal. Antibody Target: SIRT6 | SIRT6 | A synthetic peptide made to an internal region of the human SIRT6 protein | abcam ab48192 | Struhl | Human - SIRT6(ab48192)(Western blot,siRNA) | GeneCard:SIRT6 | SIRT6 (ab48192) | ||
| SIRT6_(ab62739) | Rabbit polyclonal affinity purified, raised against a synthetic peptide: GLPEIFDPPEELERK conjugated to KLH by a Cysteine residue linker, corresponding to N terminal amino acids 19-33 of Human SIRT6 | SIRT6 | NAD-dependent protein deacetylase. Has deacetylase activity towards Lys-9 and Lys-56 of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates Lys-9 of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. | abcam ab62739 | Bernstein | Human - SIRT6 (ab62739)(ChIP-seq,Western blot) | GR24519-2 | GeneCard:SIRT6 | SIRT6 (ab62739) | |
| SIX5 | Goat polyclonal IgG. Six5 (K-20) Epitope mapping near the C-terminus of Six5 of human origin. Antibody Target: SIX5 | SIX5 | The protein encoded by this gene is a homeodomain-containing transcription factor that appears to function in the regulation of organogenesis. This gene is located downstream of the dystrophia myotonica-protein kinase gene. Mutations in this geneare a cause of branchiootorenal syndrome type 2. | Santa Cruz Biotechnology sc-55706 | Myers | Human - SIX5(Western blot,IP-MassSpec) | B1408 | GeneCard:SIX5 | SIX5 (sc-55706) | |
| SLBP | Rabbit polyclonal. Antibody Target: SLBP | SLBP | Stem-loop binding protein (Homo sapiens) | Millipore 06-1376 | Tenenbaum | Human - SLBP(Immunoprecipitation,Western blot) | NRG1691091 | GeneCard:SLBP | SLBP (06-1376) | |
| Brg1 | Mouse monoclonal. Brg-1 (G-7) is raised against amino acids 209-296 mapping near the N-terminus of Brg-1 of human origin. Antibody Target: SMARCA4 | SMARCA4 | Brg1 (SMARCA4) is an ATPase subunit of the SWI/SNF chromatin-remodeling complex. | Santa Cruz Biotechnology sc-17796 | Snyder | Human - BRG1(Immunoprecipitation,IP-MassSpec) | H1104 | GeneCard:SMARCA4 | BRG1 (sc-17796) | |
| Ini1 | Goat polyclonal. Ini1 (C-20) is an affinity purified antibody raised against a peptide mapping near the C-terminus of Ini1 of human origin. Antibody Target: SMARCB1 | SMARCB1 | Ini1 (BAF47, SMARCB1) is a ubiquitous 47 kD component of the SWI/SNF chromatin-remodeling complex. | Santa Cruz Biotechnology sc-16189 | Snyder | Human - INI1(sc-16189)(Immunoprecipitation,IP-MassSpec) | C052 | GeneCard:SMARCB1 | INI1 (sc-16189) | |
| BAF155 | Rabbit polyclonal. BAF155 (H-76) is raised against amino acids 998-1073 of BAF155 of human origin. Antibody Target: SMARCC1 | SMARCC1 | BAF155 (SMARCC1, Brg1-Associated Factor, 155 kD) is a ubiquitous component of the SWI/SNF chromatin-remodeling complex. | Santa Cruz Biotechnology sc-10756 | Snyder | Human - BAF155(sc-10756)(Immunoprecipitation,IP-MassSpec) | GeneCard:SMARCC1 | BAF155 (sc-10756) | ||
| BAF170 | Rabbit polyclonal. BAF170 (H-116) is raised against amino acids 1093-1208 of BAF170 of human origin. Antibody Target: SMARCC2 | SMARCC2 | BAF170 (SMARCC2, Brg1-Associated Factor, 170 kD) is a ubiquitous component of the SWI/SNF chromatin-remodeling complex. | Santa Cruz Biotechnology sc-10757 | Snyder | Human - BAF170(sc-10757)(Immunoprecipitation,IP-MassSpec) | E0204 | GeneCard:SMARCC2 | BAF170 (sc-10757) | |
| SMC3_(ab9263) | Rabbit polyclonal affinity purified raised against synthetic peptide representing a portion within the last 100 amino acids of the human Structural Maintenance of Chromosomes-3 conjugated to KLH. Antibody Target: SMC3 | SMC3 | Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. | abcam ab9263 | Snyder | Human - SMC3(Immunoprecipitation,ChIP-seq)
Mouse - SMC3(Immunoprecipitation,ChIP-seq) |
963667 | GeneCard:SMC3 | SMC3 (ab9263) | |
| SP1 | Mouse monoclonal. Sp1(E-3) is raised against amino acids 121-345 mapping near the N-terminus of Sp1 of human origin. Antibody Target: SP1 | SP1 | SP1 is a transcription factor that binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from the serotonin receptor promoter. | Santa Cruz Biotechnology sc-17824 | Myers | Human - SP1(Immunoprecipitation-Western blot,IP-MassSpec) | K1907 | GeneCard:SP1 | SP1 (sc-17824) | |
| SP2_(SC-643) | Rabbit polyclonal IgG, epitope mapping near the N-terminus of SP2 of human origin. Antibody Target: SP2 | SP2 | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. (provided by RefSeq) | Santa Cruz Biotechnology sc-643 | Myers | Human - missing | K1803 | GeneCard:SP2 | SP2 (sc-643) | |
| SP4_(V-20) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of Sp4 of human origin. Antibody Target: SP4 | SP4 | Binds to GT and GC boxes promoters elements. Probable transcriptional activator. | Santa Cruz Biotechnology sc-645 | Myers | Human - SP4 V-20(Immunoblot) | F2609 | GeneCard:SP4 | SP4 (sc-645) | |
| PU.1 | Rabbit polyclonal IgG. Antibody Target: SPI1 | SPI1 | PU.1 (H-135) | Santa Cruz Biotechnology sc-22805 | Myers | Human - PU1(Immunoprecipitation-Western blot,IP-MassSpec) | G1009 | GeneCard:SPI1 | PU.1 (sc-22805) | |
| SREBP1 | Rabbit polyclonal affinity purified. Antibody Target: SREBP1 | SREBP1 | Sterol regulatory element binding transcription factor 1 | Santa Cruz Biotechnology sc-8984 | Snyder | Human - SREBP1 (sc-8984)(Western blot,IP-MassSpec) | 10211 | GeneCard:SREBF1 | SREBP1 (sc-8984) | |
| SREBP2 | Rabbit polyclonal affinity purified. Antibody Target: SREBP2 | SREBP2 | Sterol regulatory element binding transcription factor 2 | Cayman Chemical 10007663 | Snyder | Human - SREBP2 (10007663)(Western blot,IP-MassSpec) | 0424883-1 | GeneCard:SREBF2 | SREBP2 (10007663) | |
| SRF | Rabbit polyclonal. Antibody Target: SRF | SRF | Serum response transcription factor | Santa Cruz Biotechnology sc-335 | Myers, Wold | Human - SRF(Immunoprecipitation-Western blot,IP-MassSpec)
Mouse - missing |
F3006 L2005 H2604 | GeneCard:SRF | SRF (sc-335) | |
| STAT1 | Rabbit polyclonal affinity purified to STAT1 (alpha) p-91 (C-24). Antibody Target: STAT1 | STAT1 | transcription factor, activated by interferon signalling | Santa Cruz Biotechnology sc-345 | Snyder | Human - STAT1(Western blot,Motif Enrichment) | G2406 K2106 D2908 | GeneCard:STAT1 | STAT1 (sc-345) | |
| STAT2 | Rabbit polyclonal affinity purified. Antibody Target: STAT2 | STAT2 | peptide mapping at c-terminus of Human STAT2 p-113 (C-20) X | Santa Cruz Biotechnology sc-476X | Snyder | Human - STAT2(Immunoprecipitation,ChIP-seq) | B1908 | GeneCard:STAT2 | STAT2 (sc-476X) | |
| STAT3 | Rabbit polyclonal affinity purified. Epitope mapping at the C-terminus of Stat3 of mouse origin. Antibody Target: STAT3 | STAT3 | Member of STAT family. After phosphorylation in response to cytokines and growth factors (including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2), forms homo- or heterodimers that translocate to nucleus and activate transcription. Activates expression of a variety of genes with roles in processes such as cell growth and apoptosis. | Santa Cruz Biotechnology sc-482 | Snyder | Human - STAT3(Immunoprecipitation,IP-MassSpec) | B0111 | GeneCard:STAT3 | STAT3 (sc-482) | |
| STAT5A_(SC-74442) | Mouse monoclonal IgG. Antibody Target: STAT5A | STAT5A | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. (provided by RefSeq) | Santa Cruz Biotechnology sc-74442 | Myers | Human - STAT5A (sc-74442)(Western blot,IP-MassSpec) | G0208 | GeneCard:STAT5A | STAT5A (sc-74442) | |
| hSpt5_(sc-28678) | Rabbit polyclonal A/G affinity purified. SPT5 Antibody (H-300) epitope corresponding to amino acids 61-360 mapping near the N-terminus of SPT5 of human origin. Antibody Target: SUPT5H | SUPT5H | hSpt5 heterodimerizes with hSpt4 to form the DRB Sensitivity Inducing Factor (DSIF). DSIF play dual roles in elongation. First, in a conjunction with NELF, dephosphorylated state DSIF blocks RNA polymerase II (RNAPII) from shifting from early elongation to productive elongation. Second, after phosphorylation DSIF continues to associate with elongating RNAPII to facilitate recruitment of factors required for processing of the mRNA. | Santa Cruz Biotechnology sc-28678 | Struhl | Human - hSpt5 (sc-28678)(Western blot,Immunoprecipitation) | GeneCard:SUPT5H | hSpt5 (sc-28678) | ||
| SUZ12 | Rabbit polyclonal A/G affinity purified. Antibody Target: SUZ12 | SUZ12 | Suppressor of zeste 12 homolog, Polycomb group (PcG) protein, Component of the PRC2/EED-EZH2 complex | Dr. Peggy Farnham at USC SUZ12 | Farnham | Human - SUZ12 (Western blot,ChIP-seq) | GeneCard:SUZ12 | SUZ12 (SUZ12) | ||
| SUZ12_(05-1317) | Mouse monoclonal A/G affinity purified recombinant protein corresponding to human SUZ12. Antibody Target: SUZ12 | SUZ12 | SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. This protein is component of the PRC2 complex, which methylates Lys-9 and Lys-27 residues of histone H3. | Millipore 05-1317 | Bernstein | Human - SUZ12 (05-1317)(Western blot,ChIP-seq) | NRG1665726 | GeneCard:SUZ12 | SUZ12 (05-1317) | |
| T7Tag | Rabbit polyclonal affinity purified Anti-t7 Epitope tag, T7 (MASMTGGQQMG) from Millipore. Antibody Target: T7Tag | T7Tag | T7 (MASMTGGQQMG) | Millipore AB3790 | Tenenbaum | Human - T7-Tag (Negative Control) | NOV_69522 | Negative Control | T7Tag (AB3790) | |
| TAF1 | Mouse monoclonal (p250). Antibody Target: TAF1 | TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa. Also designated TAF250. | Santa Cruz Biotechnology sc-735 | Myers, Wold | Human - TAF1(ChIP-seq,IP-MassSpec) | K0905 F2706 G2909 | GeneCard:TAF1 | TAF1 (sc-735) | |
| TAF7_(SC-101167) | Mouse monoclonal IgG, raised against recombinant TAF II p55 (TAF7) of human origin. Antibody Target: TAF7 | TAF7 | The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II (RefSeq). | Santa Cruz Biotechnology sc-101167 | Myers | Human - TAF7 (sc-101167)(Immunoprecipitation-Western blot,IP-MassSpec) | J1509 | GeneCard:TAF7 | TAF7 (sc-101167) | |
| TAL1_(SC-12984) | Goat polyclonal antibody affinity purified; epitope mapping at the C-terminus of TAL1 of human origin. Antibody Target: TAL1 | TAL1 | TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. | Santa Cruz Biotechnology sc-12984 | Hardison, Snyder | Human - TAL1(Immunoprecipitation,IP-MassSpec)
Mouse - TAL1(Western blot) |
J2209 | GeneCard:TAL1 | TAL1 (sc-12984) | |
| TBLR1_(ab24550) | Rabbit polyclonal, immunogen: Recombinant full length protein (Human). Antibody Target: TBL1XR1 | TBL1XR1 | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. | abcam ab24550 | Snyder | Human - TBLR1 (ab24550)(Immunoprecipitation,ChIP-seq) | GR340121 | GeneCard:TBL1XR1 | TBLR1 (ab24550) | |
| TBLR1_(NB600-270) | Rabbit polyclonal affinity purified, immunogen: A synthetic peptide that maps to a region between residues 100 and 150 of human TBL1-related Protein 1 using the numbering given in SwissProt entry Q9BZK7. Antibody Target: TBL1XR1 | TBL1XR1 | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. | Novus Biologicals NB600-270 | Snyder | Human - TBLR1 (NB600-270)(Immunoprecipitation,ChIP-seq) | 1 | GeneCard:TBL1XR1 | TBLR1_(NB600-270) | |
| TBP | Mouse monoclonal affinity purified. Immunogen is synthetic peptide conjugated to KLH derived from within residues 1 - 100 of HumanTATA binding protein TBP. Antibody Target: TBP | TBP | General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. | abcam ab62126 | Snyder | Human - TBP(Immunoblot)
Mouse - TBP (ab62126)(Immunoprecipitation) |
GeneCard:TBP | TBP (ab62126) | ||
| TBP_(sc-273) | Rabbit polyclonal A/G affinity purified, raised against full length TFIID of human origin. Antibody Target: TBP | TBP | TBP is an integral subunit of the TFIID complex. TBP recognizes the TATA box and helps to recruit and orient the RNA poymerase II initiation complex and RNA polymerase III. | Santa Cruz Biotechnology sc-273 | Struhl | Human - TBP (sc-273)(Western blot,Immunoprecipitation) | GeneCard:TBP | TBP (sc-273) | ||
| TCF12 | Rabbit polyclonal IgG HEB (A-20) Epitope mapping within the C-terminus of HEB of human origin. Antibody Target: TCF12 | TCF12 | The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. | Santa Cruz Biotechnology sc-357 | Myers | Human - TCF12(Immunoprecipitation-Western blot,IP-MassSpec)
Mouse - missing |
F2305 | GeneCard:TCF12 | TCF12 (sc-357) | |
| TCF3_(SC-349) | Rabbit polyclonal. E2A.E12(V-18) is an affinity purified antibody raised against a peptide mapping at the C-terminus of E2A.E12 of human origin. Antibody Target: TCF3 | TCF3 | Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. | Santa Cruz Biotechnology sc-349 | Myers | Human - TCF3 (sc-349)(Western blot,IP-MassSpec)
Mouse - missing |
A1111 D2611 | GeneCard:TCF3 | TCF3 (sc-349) | |
| TCF7L2 | Rabbit monoclonal affinity purified. Antibody Target: TCF7L2 | TCF7L2 | TCF7L2 (formerly known as TCF4) is a member of the high mobility group (HMG) DNA binding protein family of transcription factors which consists of the following: Lymphoid enhancer factor 1 (LEF1), T Cell Factor 1 (TCF1), TCF3 and TCF4. Note: there is an official TCF-4 http://www.genecards.org/cgi-bin/carddisp.pl?gene=TCF4 | Cell Signaling Technology 2569 | Farnham | Human - TCF7L2(Immunoprecipitation,ChIP-seq) | 2 | GeneCard:TCF7L2 | TCF7L2 (2569) | |
| TCF7L2_C9B9_(2565) | Rabbit monoclonal antibody affinity purified is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu81 of human TCF7L2. Antibody Target: TCF7L2 | TCF7L2 | TCF7L2 (formerly known as TCF4) is a member of the high mobility group (HMG) DNA binding protein family of transcription factors which consists of the following: Lymphoid enhancer factor 1 (LEF1), T Cell Factor 1 (TCF1), TCF3 and TCF4. Note: there is an official TCF-4 http://www.genecards.org/cgi-bin/carddisp.pl?gene=TCF4 | Cell Signaling Technology 2565 | Farnham | Human - TCF7L2 C9B9 (2565)(Immunoprecipitation,ChIP-seq) | 3 | GeneCard:TCF7L2 | TCF7L2 C9B9 (2565) | |
| TEAD4_(SC-101184) | Mouse monoclonal IgG, raised against recombinant protein TEF-3 (TEAD4) of human origin. Antibody Target: TEAD4 | TEAD4 | Member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. | Santa Cruz Biotechnology sc-101184 | Myers | Human - TEAD4 (sc-101184)(Western blot,IP-MassSpec) | A1811 | GeneCard:TEAD4 | TEAD4 (sc-101184) | |
| AP-2alpha | Rabbit polyclonal - AP-2alpha (H-79) is a rabbit polyclonal antibody raised against amino acids 130-209 mapping within an internal region of AP-2alpha of human origin. Antibody Target: TFAP2A | TFAP2A | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5' -GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle (by similarity). | Santa Cruz Biotechnology sc-8975 | Farnham | Human - AP-2alpha (siRNA,ChIP-seq) | E0804 | GeneCard:TFAP2A | AP-2alpha (sc-8975) | |
| AP-2gamma | Rabbit polyclonal - AP-2Y (H-77) is a rabbit polyclonal antibody raised against amino acids 145-221 mapping with in an internal region of AP-2Y of human origin. Antibody Target: TFAP2C | TFAP2C | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. | Santa Cruz Biotechnology sc-8977 | Farnham | Human - AP-2gamma (siRNA,ChIP-seq) | G1404 | GeneCard:TFAP2C | AP-2gamma (sc-8977) | |
| THAP1_(SC-98174) | Goat polyclonal IgG, epitope mapping near the C-terminus of THAP1 of human origin. Antibody Target: THAP1 | THAP1 | The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. (provided by RefSeq) | Santa Cruz Biotechnology sc-98174 | Myers | Human - missing | D1910 | GeneCard:THAP1 | THAP1 (sc-98174) | |
| TP53_(SC-126) | Mouse monoclonal IgG, N-terminal epitope mapping between amino acids 11-25 of TP53 of human origin. Antibody Target: TP53 | TP53 | This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found. These variants encode distinct isoforms, which can regulate p53 transcriptional activity. (provided by RefSeq) | Santa Cruz Biotechnology sc-126 | Myers | Human - TP53 (sc-126)(Western blot,IP-MassSpec) | F0909 | GeneCard:TP53 | TP53 (sc-126) | |
| TRIM28_(SC-81411) | Mouse monoclonal IgG, raised against a recombinant protein corresponding to an internal region of TRIM28 of human origin. Antibody Target: TRIM28 | TRIM28 | The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. (provided by RefSeq) | Santa Cruz Biotechnology sc-81411 | Myers | Human - TRIM28 (sc-81411)(Western blot,IP-MassSpec) | L0309 | GeneCard:TRIM28 | TRIM28 (sc-81411) | |
| TRIM37_(SC-49548) | Goat polyclonal IgG raised against a peptide mapping at the C-terminus of TRIM37 of human origin. Antibody Target: TRIM37 | TRIM37 | This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. (provided by RefSeq) | Santa Cruz Biotechnology sc-49548 | Myers | Human - TRIM37 (sc-49548)(Western blot,IP-MassSpec) | F2507 | GeneCard:TRIM37 | TRIM37 (sc-49548) | |
| UBF_(sc-13125) | Mouse monoclonal. UBF (F-9) is raised against amino acids 1-220 of UBF of human origin. Antibody Target: UBTF | UBTF | Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 (PubMed 3413483)). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes | Santa Cruz Biotechnology sc-13125 | Snyder | Human - UBF (sc-13125)(Immunoprecipitation,ChIP-seq)
Mouse - UBF (sc-13125)(Immunoprecipitation,ChIP-seq) |
B1804 | GeneCard:UBTF | UBF (sc-13125) | |
| UBTF_(SAB1404509) | Mouse monoclonal, immunogen:UBTF (NP_055048, 551 a.a. ~ 651 a.a) partial recombinant protein with GST tag. Antibody Target: UBTF | UBTF | Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 (PubMed 3413483)). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes | Sigma-Aldrich SAB1404509 | Snyder | Human - UBTF (SAB1404509)(Immunoprecipitation,ChIP-seq) | 07219-A2 | GeneCard:UBTF | UBTF (SAB1404509) | |
| USF-1 | Rabbit polyclonal, USF-1 (C-20). Antibody Target: USF1 | USF1 | The ubiquitously expressed cellular upstream stimulatory factor (USF) consists of USF-1 and USF-2 polypeptides which independently exhibit site-specific DNA binding and are members of the c-Myc-related family of regulatory factors containing helix-loop-helix domains. USF also contains a leucine repeat that is required for efficient DNA binding. USF was originally identified as an up- stream stimulatory factor that binds the core sequence CACGTG in the adeno- virus late promoter. These findings, together with the demonstration of coop- erative interaction between USF and the initiator-binding protein, TFII-I, raises the possibility of a more general involvement of USF in transcriptional regula- tion. While expression of both USF-1 and USF-2 species is ubiquitous, different ratios of USF homo- and heterodimers are found in different cell types. | Santa Cruz Biotechnology sc-229 | Myers | Human - USF1 SC-229(Immunoprecipitation-Western blot,IP-MassSpec)
Mouse - missing |
A2109 | GeneCard:USF1 | USF1 (sc-229) | |
| USF1_(SC-8983) | Rabbit polyclonal IgG, epitope corresponding to a.a. 75-160 mapping within internal region of USF1 of human origin. Antibody Target: USF1 | USF1 | This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq). | Santa Cruz Biotechnology sc-8983 | Myers | Human - USF1 SC-8983(Immunoprecipitation-Western blot,IP-MassSpec) | E2810 | GeneCard:USF1 | USF1 (sc-8983) | |
| USF2 | Mouse monoclonal A/G affinity purified. Immunogen corresponds to amino acids 1-101 of Human USF2. Antibody Target: USF2 | USF2 | Encodes a member of the basic helix-loop-helix leucine zipper family. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs (5'-CACGTG-3'). | abcam ab60931 | Snyder | Human - USF2(Immunoprecipitation,Motif Enrichment)
Mouse - USF2 (ab60931)(Immunoprecipitation,Motif Enrichment) |
424648 | GeneCard:USF2 | USF2 (ab60931) | |
| USF2_(C-20) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of USF-2 of mouse origin. Antibody Target: USF2 | USF2 | This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene (RefSeq). | Santa Cruz Biotechnology sc-862 | Myers | Human - USF2 (C-20)(Immunoblot) | J0908 | GeneCard:USF2 | USF2 (sc-862) | |
| NSD2_(ab75359) | Mouse monoclonal affinity purified, raised against a fusion protein, corresponding to amino acids 1-647 of Human GST-WHSC1/NSD2. Antibody Target: WHSC1 | WHSC1 | This is a probable histone methyltransferase, which may act as a transcription regulator that binds DNA and suppresses IL5 transcription. | abcam ab75359 | Bernstein | Human - NSD2 (ab75359)(ChIP-seq,Western blot) | GR47579-1 | GeneCard:WHSC1 | NSD2 (ab75359) | |
| WHIP | Rabbit polyclonal affinity purified. Immunogen: (Synthetic peptide) SRESYDAPPTPSGAC conjugated to KLH, corresponding to amino acids 107-120 of Human WHIP. Antibody Target: WRNIP1 | WRNIP1 | Interacts with the N-terminal portion of Werner protein containing the exonuclease domain, shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene may influence the aging process. Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis. | abcam ab4731 | Snyder | Human - WHIP (ab4731)(Western blot,IP-MassSpec) | GeneCard:WRNIP1 | WHIP (ab4731) | ||
| XRCC4 | Rabbit polyclonal. Antibody Target: XRCC4 | XRCC4 | Recognizes the XRCC4 protein (X ray cross complementation protein). XRCC4 is a ubiquitous protein reported to have a role in DNA double-stranded break repair and in V(D)J recombination. | abcam ab145 | Snyder | Human - XRCC4(Immunoblot) | GeneCard:XRCC4 | XRCC4 (ab145) | ||
| YY1 | Rabbit polyclonal affinity purified. Antibody Target: YY1 | YY1 | YIN YANG 1 transcription factor belongs to the GLI-Kruppel class of zinc finger proteins. | Santa Cruz Biotechnology sc-1703 | Farnham, Myers | Human - YY1 (sc-1703)(Western blot,IP-MassSpec)
Human - YY1 (sc-1703)(Western blot,IP-MassSpec) |
B1710 J1909 | GeneCard:YY1 | YY1 (sc-1703) | |
| YY1_(SC-281) | Rabbit polyclonal IgG, epitope mapping at the C-terminus of YY1 of human origin. Antibody Target: YY1 | YY1 | YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1 | Santa Cruz Biotechnology sc-281 | Myers | Human - YY1 (sc-281)(Immunoprecipitation-Western blot,IP-MassSpec) | B1010 F2810 | GeneCard:YY1 | YY1 (sc-281) | |
| ZBTB33 | Mouse monoclonal IgG1. Kaiso (6F8) was raised against amino acids 1-504 representing full length Kaiso of human origin. Antibody Target: ZBTB33 | ZBTB33 | KAISO is a transcriptional regulator that binds, via its zinc fingers, to DNA sequences containing methylated CGCG or to the consensus KAISO-binding site (KBS) TCCTGCNA | Santa Cruz Biotechnology sc-23871 | Myers | Human - ZBTB33(Western blot,IP-MassSpec) | 10308 | GeneCard:ZBTB33 | ZBTB33 (sc-23871) | |
| ZBTB7A_(SC-34508) | Goat polyclonal IgG, epitope mapping at the C-terminus of LRF of human origin. Antibody Target: ZBTB7A | ZBTB7A | Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). | Santa Cruz Biotechnology sc-34508 | Myers | Human - ZBTB7A SC-34508(Immunoprecipitation-Western blot,IP-MassSpec) | H2406 | GeneCard:ZBTB7A | ZBTB7A (sc-34508) | |
| ZC3H11A_(NB100-74650) | Rabbit polyclonal antibody affinity purified. The immunogen recognized by this antibody maps to a region between residue 250 and 300 of human zinc finger CCCH-type containing 11A. | ZC3H11A | ZC3H11A is a C3H1-type zinc finger protein. ZC3H11A has been identified as a protein that is phosphorylated upon DNA damage by ATM or ATR. The function of ZC3H11A remains uncharacterized. | Novus Biologicals NB100-74650 | Snyder | Human - ZC3H11A (NB100-74650)(Immunoprecipitation,IP-MassSpec)
Mouse - ZC3H11A (NB100-74650)(Immunoprecipitation,IP-MassSpec) |
A1 | GeneCard:ZC3H11A | ZC3H11A_(NB100-74650) | |
| ZEB1_(SC-25388) | Rabbit polyclonal IgG, epitope corresponding to amino acids 39-140 mapping near the N-terminus of ZEB1 of human origin. Antibody Target: ZEB1 | ZEB1 | This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have ben associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described. (provided by RefSeq). | Santa Cruz Biotechnology sc-25388 | Myers | Human - ZEB1 (sc-25388)(Western blot,IP-MassSpec) | D2010 | GeneCard:ZEB1 | ZEB1 (sc-25388) | |
| ZKSCAN1_(HPA006672) | Rabbit polyclonal affinity purified, Immunogen: Zinc finger with KRAB and SCAN domain-containing protein 1 recombinant protein epitope signature tag (PrEST). Antibody Target: ZKSCAN1 | ZKSCAN1 | The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links. Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. | Sigma-Aldrich HPA006672 | Snyder | Human - ZKSCAN1 (HPA006672)(Immunoprecipitation,IP-MassSpec)
Mouse - ZKSCAN1 (HPA006672)(Immunoprecipitation,IP-MassSpec) |
A44630 | GeneCard:ZKSCAN1 | ZKSCAN1 (HPA006672) | |
| ZNF-MIZD-CP1_(ab65767) | Rabbit polyclonal affinity purified against synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Human Zinc finger MIZ domain-containing protein 1. Antibody Target: ZMIZ1 | ZMIZ1 | Zinc finger MIZ domain-containing protein 1 that increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. | abcam ab65767 | Snyder | Human - ZNF-MIZD-CP1 (ab65767)(Immunoprecipitation,IP-MassSpec)
Mouse - ZMIZ1 (ab65676)(Immunoprecipitation,IP-MassSpec) |
GR30927-1 | GeneCard:ZMIZ1 | ZMIZ1 (ab65767) | |
| Znf143_(16618-1-AP) | Rabbit polyclonal affinity purified against human ZNF143 (amino acids 283-626)-6his fusion protein. Antibody Target: ZNF143 | ZNF143 | Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates to efficient U6 RNA polymerase III transcription via its interaction with CHD8 | Proteintech 16618-1-AP | Snyder | Human - Znf143 (16618-1-AP)(Immunoprecipitation,IP-MassSpec) | 8059 | GeneCard:ZNF143 | ZNF143 (16618-1-AP) | |
| ZNF217 | Rabbit polyclonal antibody affinity purified raised against a recombinant ZNF217 protein corresponding to the 1562-2207 nucleotides from a human ZNF217 cDNA. Antibody Target: ZNF217 | ZNF217 | ZNF217 is an important oncogene based on the high frequency of amplification and overexpression in many cancer types, but its molecular mode of gene regulation is poorly understood. ZNF217 has been purified in complexes that contain repressor proteins such as CtBP2, suggesting that it acts as a transcriptional repressor. ZNF217 contains seven C2H2 zinc finger domains and has been shown to bind to gene promoters | Dr. Paul Yaswen at UC Berkeley ZNF217 | Farnham | Human - ZNF217 (Western blot,siRNA) | GeneCard:ZNF217 | ZNF217 (ZNF217) | ||
| ZNF263 | Mouse polyclonal. Antibody Target: ZNF263 | ZNF263 | ZNF263 (NP_005732, 201 a.a. ~ 299 a.a) partial recombinant protein with GST tag. | Novus Biologicals H00010127-A01 | Farnham | Human - ZNF263 (Western blot,siRNA) | 08212 | GeneCard:ZNF263 | ZNF263 (H00010127-A01) | |
| ZNF274 | Mouse polyclonal antibody raised against a partial recombinant ZNF274 (GST-fusion of a.a.420-531 of human ZNF274 protein). Antibody Target: ZNF274 | ZNF274 | ZNF274 is a zinc finger protein containing five C2H2-type zinc finger domains, two Kruppel-associated box A (KRABA) domains, and a leucine-rich SCAN domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. | Abnova H00010782-A01 | Farnham | Human - ZN274(Western blot,Immunoprecipitation,siRNA) | 060729QCS1 | GeneCard:ZNF274 | ZNF274 (H00010782-A01) | |
| ZNF274_(M01) | Mouse monoclonal affinity purified antibody raised against a partial recombinant ZNF274 (corresponding to amino acids 420-531 of the human ZNF274 protein). Antibody Target: ZNF274 | ZNF274 | ZNF274 is a zinc finger protein containing five C2H2-type zinc finger domains, two Kruppel-associated box A (KRABA) domains, and a leucine-rich SCAN domain. The encoded protein has been suggested to be a transcriptional repressor and interacts with the KAP1 corepressor complex. | Abnova H00010782-M01 | Farnham | Human - ZNF274 (M01)(Western blot,ChIP-seq) | 08064-4C12 | GeneCard:ZNF274 | ZNF274 (H00010782-M01) | |
| ZNF384_(HPA004051) | Rabbit polyclonal affinity purified generated using the immunogen: Zinc finger protein 384 recombinant protein epitope signature tag (PrEST) | ZNF384 | This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. | Sigma-Aldrich HPA004051 | Snyder | Human - ZNF384 (HPA004051)(Immunoprecipitation,IP-MassSpec)
Mouse - ZNF384 (HPA004051)(Immunoprecipitation,IP-MassSpec) |
A57874 | GeneCard:ZNF384 | ZNF384 (HPA004051) | |
| ZZZ3 | Rabbit polyclonal anti-human ZZZ3, Immunogen: Synthetic peptide coupled to Ovalbumin (Name PI130, sequence CGNNNGRTTDLKQQSTRESW). Antibody Target: ZZZ3 | ZZZ3 | ZZZ3 contains one ZZ-type zinc finger domain. ZZ type finger domains are named because of their ability to bind two zinc ions. These domains contain 4-6 Cys residues that participate in zinc binding (plus additional Ser/His residues), including a Cys-X2-Cys motif found in other zinc finger domains. These zinc fingers are thought to be involved in protein-protein interactions -they are most likely involved in ligand binding or molecular scaffolding. The structure of the ZZ domain shows that it belongs to the family of cross-brace zinc finger motifs that include the PHD, RING, and FYVE domains. | Dr. Lazlo Tora at Institut de Gènètique et de Biologie Molèculaire et Cellulaire ZZZ3 | Struhl | Human - missing | GeneCard:ZZZ3 | ZZZ3 | ||